Residual counter ions can stabilise a large protein complex in the gas phase

Residual counter ions can stabilise a large protein complex in the gas phase

The dual goals of retaining native solution structure in the gas phase and facilitating accurate mass measurement by mass spectrometry often require conflicting experimental parameters. Here, we use ion mobility-mass spectrometry to investigate the effects of aqueous buffer removal on the structure...

Descripció completa

Dades bibliogràfiques
Autors principals:	Freeke, J, Robinson, C, Ruotolo, B
Format:	Journal article
Idioma:	English
Publicat:	2010

Ítems similars

Gas-phase protein assemblies: Unfolding landscapes and preserving native-like structures using noncovalent adducts
per: Freeke, J, et al.
Publicat: (2012)

Ion mobility-mass spectrometry analysis of large protein complexes.
per: Ruotolo, B, et al.
Publicat: (2008)

Protein complexes in the gas phase: technology for structural genomics and proteomics.
per: Benesch, J, et al.
Publicat: (2007)

Protein complexes in the gas phase: technology for structural genomics and proteomics
per: Benesch, J, et al.
Publicat: (2007)

Gas-phase unfolding and disassembly reveals stability differences in ligand-bound multiprotein complexes.
per: Hyung, S, et al.
Publicat: (2009)

Alternate dissociation pathways identified in charge-reduced protein complex ions.
per: Pagel, K, et al.
Publicat: (2010)

Collision cross sections of proteins and their complexes: a calibration framework and database for gas-phase structural biology.
per: Bush, M, et al.
Publicat: (2010)

Ion mobility-mass spectrometry reveals long-lived, unfolded intermediates in the dissociation of protein complexes.
per: Ruotolo, B, et al.
Publicat: (2007)

Tandem differential mobility analysis-mass spectrometry reveals partial gas-phase collapse of the GroEL complex.
per: Hogan, C, et al.
Publicat: (2011)

Integrative modelling coupled with ion mobility mass spectrometry reveals structural features of the clamp loader in complex with single-stranded DNA binding protein
per: Politis, A, et al.
Publicat: (2013)

Integrative modelling coupled with ion mobility mass spectrometry reveals structural features of the clamp loader in complex with single-stranded DNA binding protein.
per: Politis, A, et al.
Publicat: (2013)

Gas-phase dissociation pathways of a tetrameric protein complex
per: Sobott, F, et al.
Publicat: (2003)

Ion mobility-mass spectrometry reveals the influence of subunit packing and charge on the dissociation of multiprotein complexes.
per: Boeri Erba, E, et al.
Publicat: (2010)

A hydrodynamic comparison of solution and gas phase proteins and their complexes.
per: Hewitt, D, et al.
Publicat: (2014)

The XP Stabiliser Formalism: a Generalisation of the Pauli Stabiliser Formalism with Arbitrary Phases
per: Mark A. Webster, et al.
Publicat: (2022-09-01)

Redox Potentials of Uranyl Ions in Macrocyclic Complexes: Quantifying the Role of Counter-Ions
per: Mahesh Sundararajan
Publicat: (2023-05-01)

Integrating ion mobility mass spectrometry with molecular modelling to determine the architecture of multiprotein complexes.
per: Politis, A, et al.
Publicat: (2010)

CLIC drive beam phase stabilisation
per: Gerbershagen, A
Publicat: (2013)

On the zwitterionic nature of gas-phase peptides and protein ions.
per: Roberto Marchese, et al.
Publicat: (2010-05-01)

Multimode ion counter
per: Aplin, K, et al.
Publicat: (2000)

Stabilising large grains in self-forming steep channels
per: W. H. Booker, et al.
Publicat: (2020-01-01)

The role of interfacial lipids in stabilising membrane protein oligomers
per: Gupta, K, et al.
Publicat: (2017)

Protein complexes in the gas phase: structural insights from ion mobility-mass spectrometry and computational modelling
per: Hall, Z, et al.
Publicat: (2013)

Aspects of native proteins are retained in vacuum.
per: Ruotolo, B, et al.
Publicat: (2006)

Status of the CLIC phase and amplitude stabilisation concept
per: Schulte, D, et al.
Publicat: (2011)

Phase-stabilised self-injection-locked microcomb
per: Thibault Wildi, et al.
Publicat: (2024-08-01)

Subunit architecture of multiprotein assemblies determined using restraints from gas-phase measurements.
per: Pukala, T, et al.
Publicat: (2009)

An infrared study of gas-phase metal nitrosyl ion-molecule complexes
per: Meizyte, G, et al.
Publicat: (2022)

Disassembly of intact multiprotein complexes in the gas phase.
per: Rostom, A, et al.
Publicat: (1999)

The effect of biopolymer stabilisation on biostimulated or bioaugmented mine residue for potential technosol production
per: Joana B. Caldeira, et al.
Publicat: (2024-10-01)

Dynamical stabilisation of complex Langevin simulations of QCD
per: Felipe Attanasio, et al.
Publicat: (2019-01-01)

Scalable quantum computing stabilised by optical tweezers on an ion crystal
per: Yu-Ching Shen, et al.
Publicat: (2020-01-01)

Flash phenomena in lime-stabilised zirconia oxide ion conductor
per: Julia Ramírez-González, et al.
Publicat: (2020-05-01)

Gas phase ion chemistry /
per: Bowers, Michael T.
Publicat: (1979)

Mistakes can stabilise the dynamics of rock-paper-scissors games.
per: Maria Kleshnina, et al.
Publicat: (2021-04-01)

How northern freshwater input can stabilise thermohaline circulation
per: Erwin Lambert, et al.
Publicat: (2016-11-01)

Spontaneous rotation can stabilise ordered chiral active fluids
per: Ananyo Maitra, et al.
Publicat: (2019-02-01)

Performance of phase noisy optical systems with frequency stabilisation
per: Young, John Scott
Publicat: (2005)

Supramolecular Tools for the Stabilisation of Blue-Phase Liquid Crystals
per: Felix Kraus, et al.
Publicat: (2022-10-01)

Silk micrococoons for protein stabilisation and molecular encapsulation
per: Vollrath, F, et al.
Publicat: (2017)