Residual counter ions can stabilise a large protein complex in the gas phase
The dual goals of retaining native solution structure in the gas phase and facilitating accurate mass measurement by mass spectrometry often require conflicting experimental parameters. Here, we use ion mobility-mass spectrometry to investigate the effects of aqueous buffer removal on the structure...
Main Authors: | Freeke, J, Robinson, C, Ruotolo, B |
---|---|
פורמט: | Journal article |
שפה: | English |
יצא לאור: |
2010
|
פריטים דומים
-
Gas-phase protein assemblies: Unfolding landscapes and preserving native-like structures using noncovalent adducts
מאת: Freeke, J, et al.
יצא לאור: (2012) -
Ion mobility-mass spectrometry analysis of large protein complexes.
מאת: Ruotolo, B, et al.
יצא לאור: (2008) -
Protein complexes in the gas phase: technology for structural genomics and proteomics.
מאת: Benesch, J, et al.
יצא לאור: (2007) -
Protein complexes in the gas phase: technology for structural genomics and proteomics
מאת: Benesch, J, et al.
יצא לאור: (2007) -
Gas-phase unfolding and disassembly reveals stability differences in ligand-bound multiprotein complexes.
מאת: Hyung, S, et al.
יצא לאור: (2009)