Hydrogen-Borrowing Alkylation of 1,2-Amino Alcohols in the Synthesis of Enantioenriched γ-Aminobutyric Acids

Hydrogen-Borrowing Alkylation of 1,2-Amino Alcohols in the Synthesis of Enantioenriched γ-Aminobutyric Acids

For the first time we have been able to employ enantiopure 1,2‐amino alcohols derived from abundant amino acids in C‐C bond forming hydrogen borrowing alkylation reactions. These reactions are facilitated by the use of the aryl ketone Ph*COMe. Racemisation of the amine stereocentre during alkylation...

書目詳細資料
Main Authors:	Hall, CJJ, Goundry, W, Donohoe, T
格式:	Journal article
語言:	English
出版:	Wiley 2021

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