Polymer stealthing and mucin-1 retargeting for enhanced pharmacokinetics of an oncolytic vaccinia virus

Polymer stealthing and mucin-1 retargeting for enhanced pharmacokinetics of an oncolytic vaccinia virus

Vaccinia Virus (VV) is a powerful tool for cancer treatment with the potential for tumour tropism, efficient cell-to-cell spread, rapid replication in cancer cells and stimulation of anti-tumour immunity. It has a well-defined safety profile and is being assessed in late-stage clinical trials. Howev...

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Dettagli Bibliografici
Autori principali:	Hill, C, Grundy, M, Bau, L, Wallington, S, Balkaran, J, Ramos, V, Fisher, K, Seymour, L, Coussios, C, Carlisle, RC
Natura:	Journal article
Lingua:	English
Pubblicazione:	Cell Press 2021

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