Polymer stealthing and mucin-1 retargeting for enhanced pharmacokinetics of an oncolytic vaccinia virus
Vaccinia Virus (VV) is a powerful tool for cancer treatment with the potential for tumour tropism, efficient cell-to-cell spread, rapid replication in cancer cells and stimulation of anti-tumour immunity. It has a well-defined safety profile and is being assessed in late-stage clinical trials. Howev...
Main Authors: | Hill, C, Grundy, M, Bau, L, Wallington, S, Balkaran, J, Ramos, V, Fisher, K, Seymour, L, Coussios, C, Carlisle, RC |
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Format: | Journal article |
Jezik: | English |
Izdano: |
Cell Press
2021
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