Mapping cis-and trans-regulatory effects across multiple tissues in twins

Mapping cis-and trans-regulatory effects across multiple tissues in twins

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Sequence-based variation in gene expression is a key driver of disease risk. Common variants regulating expression in cis have been mapped in many expression quantitative trait locus (eQTL) studies, typically in single tissues from unrelated individuals. Here, we present a comprehensive analysis of...

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Main Authors: Grundberg, E, Small, K, Hedman, A, Nica, A, Buil, A, Keildson, S, Bell, J, Yang, T, Meduri, E, Barrett, A, Nisbett, J, Sekowska, M, Wilk, A, Shin, S, Glass, D, Travers, M, Min, J, Ring, S, Ho, K, Thorleifsson, G, Kong, A, Thorsteindottir, U, Ainali, C, Dimas, A, Hassanali, N
Format: Journal article
Language:English
Published: 2012

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