Human naive CD8 T cells down-regulate expression of the WNT pathway transcription factors lymphoid enhancer binding factor 1 and transcription factor 7 (T cell factor-1) following antigen encounter in vitro and in vivo.

Human naive CD8 T cells down-regulate expression of the WNT pathway transcription factors lymphoid enhancer binding factor 1 and transcription factor 7 (T cell factor-1) following antigen encounter in vitro and in vivo.

The transcription factors lymphoid enhancer binding factor 1 (LEF1) and transcription factor 7 (TCF7) (T cell factor-1 (TCF-1)) are downstream effectors of the WNT signaling pathway, which is a critical regulator of T cell development in the thymus. In this study, we show that LEF1 and TCF7 (TCF-1)...

Ausführliche Beschreibung

Bibliographische Detailangaben
Hauptverfasser: Willinger, T, Freeman, T, Herbert, M, Hasegawa, H, Mcmichael, A, Callan, M
Format: Journal article
Sprache:English
Veröffentlicht: 2006

Ähnliche Einträge

Ähnliche Einträge