Human naive CD8 T cells down-regulate expression of the WNT pathway transcription factors lymphoid enhancer binding factor 1 and transcription factor 7 (T cell factor-1) following antigen encounter in vitro and in vivo.
The transcription factors lymphoid enhancer binding factor 1 (LEF1) and transcription factor 7 (TCF7) (T cell factor-1 (TCF-1)) are downstream effectors of the WNT signaling pathway, which is a critical regulator of T cell development in the thymus. In this study, we show that LEF1 and TCF7 (TCF-1)...
Príomhchruthaitheoirí: | Willinger, T, Freeman, T, Herbert, M, Hasegawa, H, Mcmichael, A, Callan, M |
---|---|
Formáid: | Journal article |
Teanga: | English |
Foilsithe / Cruthaithe: |
2006
|
Míreanna comhchosúla
Míreanna comhchosúla
-
T-helper Cell Type-1 Transcription Factor T-Bet Is Down-regulated in Type 1 Diabetes
de réir: Hajar Vaseghi, et al.
Foilsithe / Cruthaithe: (2016-10-01) -
Metabolic gatekeeper function of B-lymphoid transcription factors
de réir: Chan, LN, et al.
Foilsithe / Cruthaithe: (2017) -
Growth factor independent-1 maintains Notch1-dependent transcriptional programming of lymphoid precursors.
de réir: James D Phelan, et al.
Foilsithe / Cruthaithe: (2013-01-01) -
Pea3 transcription factors and wnt1-induced mouse mammary neoplasia.
de réir: Rebecca Baker, et al.
Foilsithe / Cruthaithe: (2010-01-01) -
Molecular signatures distinguish human central memory from effector memory CD8 T cell subsets.
de réir: Willinger, T, et al.
Foilsithe / Cruthaithe: (2005)