Tetrahydrobiopterin: Pleiotropic roles in cardiovascular pathophysiology

Tetrahydrobiopterin (BH4) functions as a cofactor in several important enzyme systems. Substantial evidence implicates BH4 as a key regulator of endothelial nitric oxide synthase (eNOS) in the setting of endothelial dysfunction and atherosclerosis. Investigators have now taken early steps in address...

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Bibliographic Details
Main Authors: Cunnington, C, Channon, K
Format: Journal article
Language:English
Published: 2010