Regulation of the Drosophila bHLH-PAS protein Sima by hypoxia: functional evidence for homology with mammalian HIF-1 alpha.

Hypoxia inducible factor-1 (HIF-1) is a heterodimeric complex of two basic-helix-loop-helix proteins of the PAS family which is critical for oxygen-dependent expression of many mammalian genes. Regulation is mediated by the alpha subunit (HIF-1 alpha) and sequences from HIF-1 alpha can confer hypoxi...

詳細記述

書誌詳細
主要な著者: Bacon, N, Wappner, P, O'Rourke, J, Bartlett, S, Shilo, B, Pugh, C, Ratcliffe, P
フォーマット: Journal article
言語:English
出版事項: 1998