Identification of small interfering RNA targeting Signal Transducer and Activator of Transcription 6: Characterisation and selection of candidates for pre-clinical development

Identification of small interfering RNA targeting Signal Transducer and Activator of Transcription 6: Characterisation and selection of candidates for pre-clinical development

<p style="text-align:justify;">The interleukin (IL)-13 pathway and its associated transcription factor, signal transducer and activator of transcription 6 (STAT6), have been clearly implicated in the pathogenesis of bronchial asthma. We have developed a system to effectively screen t...

Bibliografski detalji
Glavni autori:	Healey, G, Zinnen, S, Lockridge, J, Richard, I, Evans, N, Walker, W
Format:	Journal article
Izdano:	Library Publishing Media 2010

Slični predmeti

Development of pre-clinical models for evaluating the therapeutic potential of candidate siRNA targeting STAT6.
od: Gareth D Healey, i dr.
Izdano: (2014-01-01)

Small interfering RNA : new research /
od: Yamada, Kaito, i dr.
Izdano: (2009)

Inhibition of Gene Expression by Small Interfering RNA on // Signaling Pathway in Human Nasopharyngeal Carcinoma
od: Liang Zhong Yao MM, i dr.
Izdano: (2020-04-01)

Small interfering RNA against BCR-ABL transcripts sensitize mutated T315I cells to nilotinib
od: Michael Koldehoff, i dr.
Izdano: (2010-03-01)

Tumor-penetrating delivery of small interfering RNA therapeutics
od: Ren, Yin, Ph. D. Massachusetts Institute of Technology
Izdano: (2012)

Small interfering RNA inhibition of Andes virus replication.
od: Cheng-Feng Chiang, i dr.
Izdano: (2014-01-01)

Chemically modified small interfering RNA targeting Hedgehog signaling pathway for rheumatoid arthritis therapy
od: Lang Lin, i dr.
Izdano: (2023-03-01)

Small interfering RNA against transcription factor STAT6 leads to increased cholesterol synthesis in lung cancer cell lines.
od: Richa Dubey, i dr.
Izdano: (2011-01-01)

An Atelocollagen Coating for Efficient Local Gene Silencing by Using Small Interfering RNA
od: Olivia Koenig, i dr.
Izdano: (2017-03-01)

Small interfering RNA: potential in real-world clinical practice
od: A. S. Motrinchuk, i dr.
Izdano: (2024-04-01)

Cholesterol Conjugates of Small Interfering RNA: Linkers and Patterns of Modification
od: Ivan V. Chernikov, i dr.
Izdano: (2024-02-01)

Phenotypic Alteration of BMDM In Vitro Using Small Interfering RNA
od: Noreen Halimani, i dr.
Izdano: (2022-08-01)

Potential Application of Small Interfering RNA in Gastro-Intestinal Tumors
od: Pasquale Losurdo, i dr.
Izdano: (2022-10-01)

Small Interfering RNA for Gliomas Treatment: Overcoming Hurdles in Delivery
od: Xin-Qi Teng, i dr.
Izdano: (2022-07-01)

Small Interfering RNA in Colorectal Cancer Liver Metastasis Therapy
od: Junlin Xie MM, i dr.
Izdano: (2022-07-01)

Small Interfering RNA Therapeutics in Hypertension: A Viewpoint on Vasopressor and Vasopressor‐Sparing Strategies for Counteracting Blood Pressure Lowering by Angiotensinogen–Targeting Small Interfering RNA
od: Priyanga Ranasinghe, i dr.
Izdano: (2022-10-01)

Small Interfering RNA Efficiently Suppresses Adhesion Molecule Expression on Pulmonary Microvascular Endothelium
od: Tobias Walker, i dr.
Izdano: (2011-01-01)

Signal transducers and activators of transcription (STATs) : activation and biology /
od: Sehgal, Pravinkumar B., i dr.
Izdano: (2003)

Porous silicon nanotube bundles as nanocarriers for small interfering RNA delivery
od: Nguyen T. Le, i dr.
Izdano: (2024-08-01)

Delivery of Thrombospondin-2 Small Interfering RNA for Suppression of Intimal Hyperplasia
od: Jennifer R. Li, i dr.
Izdano: (2021-01-01)

Secondary Small Interfering RNA-Based Silencing Tools in Plants: An Update
od: Alberto Carbonell
Izdano: (2019-05-01)

Inclisiran—Safety and Effectiveness of Small Interfering RNA in Inhibition of PCSK-9
od: Łukasz Wołowiec, i dr.
Izdano: (2023-01-01)

Delivery of therapeutic small interfering RNA: The current patent-based landscape
od: Yu Chen, i dr.
Izdano: (2022-09-01)

Nanoparticle-based delivery of small interfering RNA: challenges for cancer therapy
od: Miele E, i dr.
Izdano: (2012-07-01)

Transcription factor signal transducer and activator of transcription 6 (STAT6) is an inhibitory factor for adult myogenesis
od: Mitsutoshi Kurosaka, i dr.
Izdano: (2021-05-01)

Pre-Clinical and Clinical Applications of Small Interfering RNAs (siRNA) and Co-Delivery Systems for Pancreatic Cancer Therapy
od: Sepideh Mirzaei, i dr.
Izdano: (2021-11-01)

Colored petri net modeling of small interfering RNA-mediated messenger RNA degradation
od: Niloofar Nickaeen, i dr.
Izdano: (2016-01-01)

Small interfering RNA (siRNA): a hope for the loss-of-function studies in anesthesiology?
od: Yun Hong Kim
Izdano: (2010-12-01)

A small interfering RNA (siRNA) database for SARS-CoV-2
od: Inácio Gomes Medeiros, i dr.
Izdano: (2021-04-01)

Virus-Derived Small Interfering RNAs Affect the Accumulations of Viral and Host Transcripts in Maize
od: Zihao Xia, i dr.
Izdano: (2018-11-01)

Signal transducers and activators of transcription 6 (Stat6) variants in childhood and adult asthma
od: Michiko Suzuki, i dr.
Izdano: (2004-01-01)

Clinical application of small interfering RNA in cardiovascular diseases: A bibliometric analysis
od: Jialian Lv, i dr.
Izdano: (2025-03-01)

siRNAEfficacyDB: An experimentally supported small interfering RNA efficacy database
od: Yang Zhang, i dr.
Izdano: (2024-12-01)

The potential of synthetic small interfering RNA-based antiviral drugs for influenza treatment
od: E. A. Pashkov, i dr.
Izdano: (2020-09-01)

An efficient intrathecal delivery of small interfering RNA to the spinal cord and peripheral neurons
od: Porreca Frank, i dr.
Izdano: (2005-09-01)

Inhibitory effect of small interfering RNA on dengue virus replication in mosquito cells
od: Li Lei, i dr.
Izdano: (2010-10-01)

Alpha-synuclein suppression by targeted small interfering RNA in the primate substantia nigra.
od: Alison L McCormack, i dr.
Izdano: (2010-01-01)

Small interfering RNA-producing loci in the ancient parasitic eukaryote <it>Trypanosoma brucei</it>
od: Tschudi Christian, i dr.
Izdano: (2012-08-01)

Interfering RNA and HIV: reciprocal interferences.
od: Pierre Corbeau
Izdano: (2008-01-01)

Tospoviruses Induce Small Interfering RNAs Targeting Viral Sequences and Endogenous Transcripts in Solanaceous Plants
od: Stephen J. Fletcher, i dr.
Izdano: (2022-06-01)