Identification of small interfering RNA targeting Signal Transducer and Activator of Transcription 6: Characterisation and selection of candidates for pre-clinical development

Identification of small interfering RNA targeting Signal Transducer and Activator of Transcription 6: Characterisation and selection of candidates for pre-clinical development

<p style="text-align:justify;">The interleukin (IL)-13 pathway and its associated transcription factor, signal transducer and activator of transcription 6 (STAT6), have been clearly implicated in the pathogenesis of bronchial asthma. We have developed a system to effectively screen t...

Бүрэн тодорхойлолт

Номзүйн дэлгэрэнгүй
Үндсэн зохиолчид:	Healey, G, Zinnen, S, Lockridge, J, Richard, I, Evans, N, Walker, W
Формат:	Journal article
Хэвлэсэн:	Library Publishing Media 2010

Ижил төстэй зүйлс

Development of pre-clinical models for evaluating the therapeutic potential of candidate siRNA targeting STAT6.
-н: Gareth D Healey, зэрэг
Хэвлэсэн: (2014-01-01)

Small interfering RNA : new research /
-н: Yamada, Kaito, зэрэг
Хэвлэсэн: (2009)

Small interfering RNA against BCR-ABL transcripts sensitize mutated T315I cells to nilotinib
-н: Michael Koldehoff, зэрэг
Хэвлэсэн: (2010-03-01)

Tumor-penetrating delivery of small interfering RNA therapeutics
-н: Ren, Yin, Ph. D. Massachusetts Institute of Technology
Хэвлэсэн: (2012)

Small interfering RNA inhibition of Andes virus replication.
-н: Cheng-Feng Chiang, зэрэг
Хэвлэсэн: (2014-01-01)

An Atelocollagen Coating for Efficient Local Gene Silencing by Using Small Interfering RNA
-н: Olivia Koenig, зэрэг
Хэвлэсэн: (2017-03-01)

Small interfering RNA: potential in real-world clinical practice
-н: A. S. Motrinchuk, зэрэг
Хэвлэсэн: (2024-04-01)

Cholesterol Conjugates of Small Interfering RNA: Linkers and Patterns of Modification
-н: Ivan V. Chernikov, зэрэг
Хэвлэсэн: (2024-02-01)

Phenotypic Alteration of BMDM In Vitro Using Small Interfering RNA
-н: Noreen Halimani, зэрэг
Хэвлэсэн: (2022-08-01)

Potential Application of Small Interfering RNA in Gastro-Intestinal Tumors
-н: Pasquale Losurdo, зэрэг
Хэвлэсэн: (2022-10-01)

Small Interfering RNA for Gliomas Treatment: Overcoming Hurdles in Delivery
-н: Xin-Qi Teng, зэрэг
Хэвлэсэн: (2022-07-01)

Small Interfering RNA in Colorectal Cancer Liver Metastasis Therapy
-н: Junlin Xie MM, зэрэг
Хэвлэсэн: (2022-07-01)

Small Interfering RNA Therapeutics in Hypertension: A Viewpoint on Vasopressor and Vasopressor‐Sparing Strategies for Counteracting Blood Pressure Lowering by Angiotensinogen–Targeting Small Interfering RNA
-н: Priyanga Ranasinghe, зэрэг
Хэвлэсэн: (2022-10-01)

Small Interfering RNA Efficiently Suppresses Adhesion Molecule Expression on Pulmonary Microvascular Endothelium
-н: Tobias Walker, зэрэг
Хэвлэсэн: (2011-01-01)

Transcription factor signal transducer and activator of transcription 6 (STAT6) is an inhibitory factor for adult myogenesis
-н: Mitsutoshi Kurosaka, зэрэг
Хэвлэсэн: (2021-05-01)

Signal transducers and activators of transcription 6 (Stat6) variants in childhood and adult asthma
-н: Michiko Suzuki, зэрэг
Хэвлэсэн: (2004-01-01)

Inhibition of Gene Expression by Small Interfering RNA on // Signaling Pathway in Human Nasopharyngeal Carcinoma
-н: Liang Zhong Yao MM, зэрэг
Хэвлэсэн: (2020-04-01)

Porous silicon nanotube bundles as nanocarriers for small interfering RNA delivery
-н: Nguyen T. Le, зэрэг
Хэвлэсэн: (2024-08-01)

Delivery of Thrombospondin-2 Small Interfering RNA for Suppression of Intimal Hyperplasia
-н: Jennifer R. Li, зэрэг
Хэвлэсэн: (2021-01-01)

Secondary Small Interfering RNA-Based Silencing Tools in Plants: An Update
-н: Alberto Carbonell
Хэвлэсэн: (2019-05-01)

Inclisiran—Safety and Effectiveness of Small Interfering RNA in Inhibition of PCSK-9
-н: Łukasz Wołowiec, зэрэг
Хэвлэсэн: (2023-01-01)

Delivery of therapeutic small interfering RNA: The current patent-based landscape
-н: Yu Chen, зэрэг
Хэвлэсэн: (2022-09-01)

Nanoparticle-based delivery of small interfering RNA: challenges for cancer therapy
-н: Miele E, зэрэг
Хэвлэсэн: (2012-07-01)

Colored petri net modeling of small interfering RNA-mediated messenger RNA degradation
-н: Niloofar Nickaeen, зэрэг
Хэвлэсэн: (2016-01-01)

Small interfering RNA (siRNA): a hope for the loss-of-function studies in anesthesiology?
-н: Yun Hong Kim
Хэвлэсэн: (2010-12-01)

Pre-Clinical and Clinical Applications of Small Interfering RNAs (siRNA) and Co-Delivery Systems for Pancreatic Cancer Therapy
-н: Sepideh Mirzaei, зэрэг
Хэвлэсэн: (2021-11-01)

Small interfering RNA silencing of interleukin-6 in mesenchymal stromal cells inhibits multiple myeloma cell growth
-н: Teoh, Hoon Koon, зэрэг
Хэвлэсэн: (2016)

Virus-Derived Small Interfering RNAs Affect the Accumulations of Viral and Host Transcripts in Maize
-н: Zihao Xia, зэрэг
Хэвлэсэн: (2018-11-01)

Chemically modified small interfering RNA targeting Hedgehog signaling pathway for rheumatoid arthritis therapy
-н: Lang Lin, зэрэг
Хэвлэсэн: (2023-03-01)

Clinical application of small interfering RNA in cardiovascular diseases: A bibliometric analysis
-н: Jialian Lv, зэрэг
Хэвлэсэн: (2025-03-01)

siRNAEfficacyDB: An experimentally supported small interfering RNA efficacy database
-н: Yang Zhang, зэрэг
Хэвлэсэн: (2024-12-01)

The potential of synthetic small interfering RNA-based antiviral drugs for influenza treatment
-н: E. A. Pashkov, зэрэг
Хэвлэсэн: (2020-09-01)

An efficient intrathecal delivery of small interfering RNA to the spinal cord and peripheral neurons
-н: Porreca Frank, зэрэг
Хэвлэсэн: (2005-09-01)

Inhibitory effect of small interfering RNA on dengue virus replication in mosquito cells
-н: Li Lei, зэрэг
Хэвлэсэн: (2010-10-01)

Alpha-synuclein suppression by targeted small interfering RNA in the primate substantia nigra.
-н: Alison L McCormack, зэрэг
Хэвлэсэн: (2010-01-01)

Interfering RNA and HIV: reciprocal interferences.
-н: Pierre Corbeau
Хэвлэсэн: (2008-01-01)

Tospoviruses Induce Small Interfering RNAs Targeting Viral Sequences and Endogenous Transcripts in Solanaceous Plants
-н: Stephen J. Fletcher, зэрэг
Хэвлэсэн: (2022-06-01)

Transcript imaging and candidate gene strategy for the characterisation of Prunus/PPV interactions
-н: V. Decroocq, зэрэг
Хэвлэсэн: (2002-06-01)

Small interfering RNA (siRNA)-based therapeutic applications against viruses: principles, potential, and challenges
-н: Hara Kang, зэрэг
Хэвлэсэн: (2023-10-01)

Small Interfering RNA Targeted to ASPP2 Promotes Progression of Experimental Proliferative Vitreoretinopathy
-н: Xiao-Li Chen, зэрэг
Хэвлэсэн: (2016-01-01)