Cognitive changes after carotid artery stenting.

INTRODUCTION: We aimed to test changes in cognitive performance after carotid artery stenting (CAS). METHOD: Ten patients were neuropsychologically tested at least 24 h before and 48 h after CAS. To diminish thromboembolic events, we used a proximal protection device. The following neuropsychologica...

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Auteurs principaux: Grunwald, I, Supprian, T, Politi, M, Struffert, T, Falkai, P, Krick, C, Backens, M, Reith, W
Format: Journal article
Langue:English
Publié: 2006
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author Grunwald, I
Supprian, T
Politi, M
Struffert, T
Falkai, P
Krick, C
Backens, M
Reith, W
author_facet Grunwald, I
Supprian, T
Politi, M
Struffert, T
Falkai, P
Krick, C
Backens, M
Reith, W
author_sort Grunwald, I
collection OXFORD
description INTRODUCTION: We aimed to test changes in cognitive performance after carotid artery stenting (CAS). METHOD: Ten patients were neuropsychologically tested at least 24 h before and 48 h after CAS. To diminish thromboembolic events, we used a proximal protection device. The following neuropsychological tests were selected: The Mini Mental State Examination (MMSE), symbol digit test and subtests of the Consortium to Establish a Registry for Alzheimer's Disease (CERAD) battery (verbal fluency, constructional practice, word list memory and delayed recall). Affective state was determined by the Beck Depression Score (BDS). RESULTS: No patient suffered from depression (BDS <1) or dementia (MMSE 29.9+/-1.5). Nine of the ten patients (P=0.12) showed increased speed in the Number Connection Test (NCT) (corresponding to trail making test). Most patients showed better or similar results concerning delayed recall (P=0.31). No change was observed in the symbol digit test, word list memory, verbal fluency or constructional practice. Better results concerning NCT and delayed recall after carotid stenting might be due to improved brain perfusion. CONCLUSION: After CAS, cognitive and memory performance seem to improve. Further studies with different time intervals and more refined testing, as well as perfusion-weighted imaging, are needed.
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spelling oxford-uuid:6b7d1263-654e-47fc-a59f-fa5edf5e73d32022-03-26T19:04:26ZCognitive changes after carotid artery stenting.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:6b7d1263-654e-47fc-a59f-fa5edf5e73d3EnglishSymplectic Elements at Oxford2006Grunwald, ISupprian, TPoliti, MStruffert, TFalkai, PKrick, CBackens, MReith, WINTRODUCTION: We aimed to test changes in cognitive performance after carotid artery stenting (CAS). METHOD: Ten patients were neuropsychologically tested at least 24 h before and 48 h after CAS. To diminish thromboembolic events, we used a proximal protection device. The following neuropsychological tests were selected: The Mini Mental State Examination (MMSE), symbol digit test and subtests of the Consortium to Establish a Registry for Alzheimer's Disease (CERAD) battery (verbal fluency, constructional practice, word list memory and delayed recall). Affective state was determined by the Beck Depression Score (BDS). RESULTS: No patient suffered from depression (BDS <1) or dementia (MMSE 29.9+/-1.5). Nine of the ten patients (P=0.12) showed increased speed in the Number Connection Test (NCT) (corresponding to trail making test). Most patients showed better or similar results concerning delayed recall (P=0.31). No change was observed in the symbol digit test, word list memory, verbal fluency or constructional practice. Better results concerning NCT and delayed recall after carotid stenting might be due to improved brain perfusion. CONCLUSION: After CAS, cognitive and memory performance seem to improve. Further studies with different time intervals and more refined testing, as well as perfusion-weighted imaging, are needed.
spellingShingle Grunwald, I
Supprian, T
Politi, M
Struffert, T
Falkai, P
Krick, C
Backens, M
Reith, W
Cognitive changes after carotid artery stenting.
title Cognitive changes after carotid artery stenting.
title_full Cognitive changes after carotid artery stenting.
title_fullStr Cognitive changes after carotid artery stenting.
title_full_unstemmed Cognitive changes after carotid artery stenting.
title_short Cognitive changes after carotid artery stenting.
title_sort cognitive changes after carotid artery stenting
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