Cytokine blockade in rheumatoid arthritis.
As we enter the 2000's it is clear that cytokine blockade is an effective therapeutic strategy for rheumatoid arthritis. In this brief review, we will review the rationale for anti TNFalpha therapy, the current status of therapy and focus on the regulation of TNFalpha production in rheumatoid s...
| Main Authors: | , , , , , |
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| Format: | Journal article |
| Language: | English |
| Published: |
2001
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| _version_ | 1797073979260796928 |
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| author | Feldmann, M Maini, R Bondeson, J Taylor, P Foxwell, B Brennan, F |
| author_facet | Feldmann, M Maini, R Bondeson, J Taylor, P Foxwell, B Brennan, F |
| author_sort | Feldmann, M |
| collection | OXFORD |
| description | As we enter the 2000's it is clear that cytokine blockade is an effective therapeutic strategy for rheumatoid arthritis. In this brief review, we will review the rationale for anti TNFalpha therapy, the current status of therapy and focus on the regulation of TNFalpha production in rheumatoid synovium. New approaches to studying TNF regulation in RA and of elucidating the controversial role of T cells in this complex disease will be described. |
| first_indexed | 2024-03-06T23:29:42Z |
| format | Journal article |
| id | oxford-uuid:6b9acc0e-ef94-4760-b8b2-66d5488c32c0 |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-06T23:29:42Z |
| publishDate | 2001 |
| record_format | dspace |
| spelling | oxford-uuid:6b9acc0e-ef94-4760-b8b2-66d5488c32c02022-03-26T19:05:08ZCytokine blockade in rheumatoid arthritis.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:6b9acc0e-ef94-4760-b8b2-66d5488c32c0EnglishSymplectic Elements at Oxford2001Feldmann, MMaini, RBondeson, JTaylor, PFoxwell, BBrennan, FAs we enter the 2000's it is clear that cytokine blockade is an effective therapeutic strategy for rheumatoid arthritis. In this brief review, we will review the rationale for anti TNFalpha therapy, the current status of therapy and focus on the regulation of TNFalpha production in rheumatoid synovium. New approaches to studying TNF regulation in RA and of elucidating the controversial role of T cells in this complex disease will be described. |
| spellingShingle | Feldmann, M Maini, R Bondeson, J Taylor, P Foxwell, B Brennan, F Cytokine blockade in rheumatoid arthritis. |
| title | Cytokine blockade in rheumatoid arthritis. |
| title_full | Cytokine blockade in rheumatoid arthritis. |
| title_fullStr | Cytokine blockade in rheumatoid arthritis. |
| title_full_unstemmed | Cytokine blockade in rheumatoid arthritis. |
| title_short | Cytokine blockade in rheumatoid arthritis. |
| title_sort | cytokine blockade in rheumatoid arthritis |
| work_keys_str_mv | AT feldmannm cytokineblockadeinrheumatoidarthritis AT mainir cytokineblockadeinrheumatoidarthritis AT bondesonj cytokineblockadeinrheumatoidarthritis AT taylorp cytokineblockadeinrheumatoidarthritis AT foxwellb cytokineblockadeinrheumatoidarthritis AT brennanf cytokineblockadeinrheumatoidarthritis |