Eisosome-driven plasma membrane organization is mediated by BAR domains.
Plasma membranes are organized into domains of different protein and lipid composition. Eisosomes are key complexes for yeast plasma membrane organization, containing primarily Pil1 and Lsp1. Here we show that both proteins consist mostly of a banana-shaped BAR domain common to membrane sculpting pr...
| Main Authors: | , , , , |
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| Format: | Journal article |
| Language: | English |
| Published: |
2011
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| _version_ | 1826277492437024768 |
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| author | Ziółkowska, N Karotki, L Rehman, M Huiskonen, J Walther, T |
| author_facet | Ziółkowska, N Karotki, L Rehman, M Huiskonen, J Walther, T |
| author_sort | Ziółkowska, N |
| collection | OXFORD |
| description | Plasma membranes are organized into domains of different protein and lipid composition. Eisosomes are key complexes for yeast plasma membrane organization, containing primarily Pil1 and Lsp1. Here we show that both proteins consist mostly of a banana-shaped BAR domain common to membrane sculpting proteins, most similar to the ones of amphiphysin, arfaptin 2 and endophilin 2. Our data reveal a previously unrecognized family of BAR-domain proteins involved in plasma membrane organization. |
| first_indexed | 2024-03-06T23:29:43Z |
| format | Journal article |
| id | oxford-uuid:6b9ccdac-2c90-4c54-9050-4274585e6102 |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-06T23:29:43Z |
| publishDate | 2011 |
| record_format | dspace |
| spelling | oxford-uuid:6b9ccdac-2c90-4c54-9050-4274585e61022022-03-26T19:05:09ZEisosome-driven plasma membrane organization is mediated by BAR domains.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:6b9ccdac-2c90-4c54-9050-4274585e6102EnglishSymplectic Elements at Oxford2011Ziółkowska, NKarotki, LRehman, MHuiskonen, JWalther, TPlasma membranes are organized into domains of different protein and lipid composition. Eisosomes are key complexes for yeast plasma membrane organization, containing primarily Pil1 and Lsp1. Here we show that both proteins consist mostly of a banana-shaped BAR domain common to membrane sculpting proteins, most similar to the ones of amphiphysin, arfaptin 2 and endophilin 2. Our data reveal a previously unrecognized family of BAR-domain proteins involved in plasma membrane organization. |
| spellingShingle | Ziółkowska, N Karotki, L Rehman, M Huiskonen, J Walther, T Eisosome-driven plasma membrane organization is mediated by BAR domains. |
| title | Eisosome-driven plasma membrane organization is mediated by BAR domains. |
| title_full | Eisosome-driven plasma membrane organization is mediated by BAR domains. |
| title_fullStr | Eisosome-driven plasma membrane organization is mediated by BAR domains. |
| title_full_unstemmed | Eisosome-driven plasma membrane organization is mediated by BAR domains. |
| title_short | Eisosome-driven plasma membrane organization is mediated by BAR domains. |
| title_sort | eisosome driven plasma membrane organization is mediated by bar domains |
| work_keys_str_mv | AT ziołkowskan eisosomedrivenplasmamembraneorganizationismediatedbybardomains AT karotkil eisosomedrivenplasmamembraneorganizationismediatedbybardomains AT rehmanm eisosomedrivenplasmamembraneorganizationismediatedbybardomains AT huiskonenj eisosomedrivenplasmamembraneorganizationismediatedbybardomains AT walthert eisosomedrivenplasmamembraneorganizationismediatedbybardomains |