Residue-selective protein C-formylation via sequential difluoroalkylation-hydrolysis

Residue-selective protein C-formylation via sequential difluoroalkylation-hydrolysis

The carbonyl group is now a widely useful, nonproteinogenic functional group in chemical biology, yet methods for its generation in proteins have relied upon either cotranslational incorporation of unnatural amino acids bearing carbonyls or oxidative conversion (chemical or enzymatic) of existing na...

Fuld beskrivelse

Bibliografiske detaljer
Main Authors:	Imiołek, M, Isenegger, PG, Ng, W-L, Khan, A, Gouverneur, V, Davis, BG
Format:	Journal article
Sprog:	English
Udgivet:	American Chemical Society 2021

Lignende værker

Residue-Selective Protein C‑Formylation via Sequential Difluoroalkylation-Hydrolysis
af: Mateusz Imiołek, et al.
Udgivet: (2021-01-01)

Selective radical trifluoromethylation of native residues in proteins
af: Imiołek, M, et al.
Udgivet: (2018)

Posttranslational, site-directed photochemical fluorine editing of protein sidechains to probe residue oxidation state via 19F-nuclear magnetic resonance
af: Isenegger, PG, et al.
Udgivet: (2023)

Copper-Catalyzed Difluoroalkylation Reaction
af: Dao-Qing Dong, et al.
Udgivet: (2022-12-01)

Radical chemistry for selective modification of native residues in proteins
af: Imiolek, M
Udgivet: (2020)

Photo-mediated para-selective C(sp2)−H difluoroalkylations
af: Yi Luo, et al.
Udgivet: (2025-02-01)

Synthesis of β-difluoroalkyl azides via elusive 1,2-azide migration
af: Ning, y, et al.
Udgivet: (2019)

Synthesis of enones, pyrazolines and pyrrolines with gem-difluoroalkyl side chains
af: Assaad Nasr El Dine, et al.
Udgivet: (2013-09-01)

Difluoroalkylation of tertiary amides and lactams by an iridium-catalyzed reductive reformatsky reaction
af: Biallas, P, et al.
Udgivet: (2022)

Copper‐Catalyzed Regio‐ and Enantioselective Hydroboration of Difluoroalkyl‐Substituted Internal Alkenes
af: Tao‐Qian Zhao, et al.
Udgivet: (2023-12-01)

Catalytic Asymmetric Difluoroalkylation Using In Situ Generated Difluoroenol Species as the Privileged Synthon
af: Xiongda Xie, et al.
Udgivet: (2024-04-01)

Concepts of catalysis in site-selective protein modifications
af: Isenegger, P, et al.
Udgivet: (2019)

Post-translational insertion of boron in proteins to probe and modulate function
af: Mollner, TA, et al.
Udgivet: (2021)

CF2H-synthon enables asymmetric radical difluoroalkylation for synthesis of chiral difluoromethylated amines
af: Peng Liu, et al.
Udgivet: (2025-01-01)

Palladium-Catalyzed Intramolecular C-H Difluoroalkylation: Synthesis of Substituted 3,3-Difluoro-2-oxindoles
af: Shi, Shi-Liang, et al.
Udgivet: (2015)

Formylation of Amines
af: Ciera J. Gerack, et al.
Udgivet: (2014-06-01)

Uncommon reaction in 4-formyl phenols – substitution of the formyl group
af: Eleana Lopušanskaja, et al.
Udgivet: (2023-09-01)

A Sequential Combination of Laccase Pretreatment and Enzymatic Hydrolysis for Glucose Production from Furfural Residues
af: Hailong Yu, et al.
Udgivet: (2014-06-01)

The spectroscopy of the formyl radical
af: Adamson, George William
Udgivet: (2005)

Production of an extensive sunflower protein hydrolysate by sequential hydrolysis with endo- and exo-proteases.
af: Alvaro Villanueva, et al.
Udgivet: (1999-12-01)

N⁶-formylation of lysine : a pathological secondary modification of proteins
af: Edrissi, Bahar
Udgivet: (2013)

Formyl peptide receptor 2 activation by mitochondrial formyl peptides stimulates the neutrophil proinflammatory response via the ERK pathway and exacerbates ischemia–reperfusion injury
af: Yirui Cao, et al.
Udgivet: (2023-01-01)

Imaging of translocator protein upregulation is selective for pro‐inflammatory polarized astrocytes and microglia
af: Pannell, M, et al.
Udgivet: (2019)

Formyl-methionine as a degradation signal at the N-termini of bacterial proteins
af: Konstantin I. Piatkov, et al.
Udgivet: (2015-09-01)

18F-trifluoromethanesulfinate enables direct C–H 18F-trifluoromethylation of native aromatic residues in peptides
af: Kee, C, et al.
Udgivet: (2020)

Antiflammin-2 Activates the Human Formyl-Peptide Receptor Like 1
af: Ahmad M. Kamal, et al.
Udgivet: (2006-01-01)

Polycotton waste textile recycling by sequential hydrolysis and glycolysis
af: Nienke Leenders, et al.
Udgivet: (2025-01-01)

Honokiol suppresses formyl peptide-induced human neutrophil activation by blocking formyl peptide receptor 1
af: Fu-Chao Liu, et al.
Udgivet: (2017-07-01)

Formylation of metallocomplexes of p- and m-tetraanizylporphyrins
af: S. V. Tsukanov, et al.
Udgivet: (2006-08-01)

2-Formyl-6-methoxyphenyl cinnamate
af: N. Manikandan, et al.
Udgivet: (2012-07-01)

4-Formyl-2-nitrophenyl benzoate
af: Rodolfo Moreno-Fuquen, et al.
Udgivet: (2014-03-01)

Immunotherapeutic potential of n-terminally formylated ESAT-6 protein in murine tuberculosis
af: Shabir Ahmad Mir, et al.
Udgivet: (2022-01-01)

Role of <it>N</it>-terminal protein formylation in central metabolic processes in <it>Staphylococcus aureus</it>
af: Mader Diana, et al.
Udgivet: (2013-01-01)

Sequential Hydrolysis of Chicken Feathers Composed of Ultrasound and Enzymatic Steps: An Enhanced Protein Source with Bioactive Peptides
af: Nely de Almeida Pedrosa, et al.
Udgivet: (2022-09-01)

Copper(II)-Catalyzed Selective CAr-H Bond Formylation: Synthesis of Dialdehyde Aniline
af: Shiwei Guo, et al.
Udgivet: (2022-05-01)

Twice as Nice: The Duff Formylation of Umbelliferone Revised
af: Vladislav V. Skarga, et al.
Udgivet: (2021-12-01)

Promiscuous Receptors and Neuroinflammation: The Formyl Peptide Class
af: Edward S. Wickstead, et al.
Udgivet: (2022-12-01)

4-Formyl-2-nitrophenyl 2-chlorobenzoate
af: Juan C. Tenorio, et al.
Udgivet: (2013-12-01)

Studies on the Properties of the Sporulation Specific Protein Dit1 and Its Product Formyl Tyrosine
af: Mostafa Basiony, et al.
Udgivet: (2020-06-01)

The G-Protein Coupled Formyl Peptide Receptors and Their Role in the Progression of Digestive Tract Cancer
af: Cuimeng Tian MD, et al.
Udgivet: (2020-11-01)