Residue-selective protein C-formylation via sequential difluoroalkylation-hydrolysis

Residue-selective protein C-formylation via sequential difluoroalkylation-hydrolysis

The carbonyl group is now a widely useful, nonproteinogenic functional group in chemical biology, yet methods for its generation in proteins have relied upon either cotranslational incorporation of unnatural amino acids bearing carbonyls or oxidative conversion (chemical or enzymatic) of existing na...

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Bibliographic Details
Main Authors:	Imiołek, M, Isenegger, PG, Ng, W-L, Khan, A, Gouverneur, V, Davis, BG
Format:	Journal article
Language:	English
Published:	American Chemical Society 2021

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