Redox sensor and effector functions of tetrahydrobiopterin and the mitochondria in molecular models of cardiovascular disease
<p>Tetrahydrobiopterin (BH<sub>4</sub>) is a redox active molecule that is essential for the production of nitric oxide (NO) by the NO synthase (NOS) enzymes. Loss of endothelial BH<sub>4</sub> leads to decreased NO and increased superoxide generation by endothelial NOS...
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| Format: | Thesis |
| Language: | English |
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2018
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