The topology of transcription by immobilized polymerases.
Current models for RNA synthesis involve an RNA polymerase that tracks along a static template. However, research on chromatin loops suggests that the template slides past a polymerase immobilized in a large transcription factory. The evidence for immobilized polymerases is reviewed, and a model for...
Main Authors: | , , , , |
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Format: | Conference item |
Published: |
1996
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