The topology of transcription by immobilized polymerases.
Current models for RNA synthesis involve an RNA polymerase that tracks along a static template. However, research on chromatin loops suggests that the template slides past a polymerase immobilized in a large transcription factory. The evidence for immobilized polymerases is reviewed, and a model for...
Glavni autori: | Iborra, F, Pombo, A, McManus, J, Jackson, D, Cook, P |
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Format: | Conference item |
Izdano: |
1996
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Slični predmeti
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Transcription by an immobilized RNA polymerase from bacteriophage T7 and the topology of transcription.
od: Cook, P, i dr.
Izdano: (1992) -
Active RNA polymerases are localized within discrete transcription "factories' in human nuclei.
od: Iborra, F, i dr.
Izdano: (1996) -
Transcription factories and chromosome structure
od: Pombo, A, i dr.
Izdano: (1997) -
Nuclear factories for replication, transcription and repair
od: McManus, J, i dr.
Izdano: (1995) -
Numbers and organization of RNA polymerases, nascent transcripts, and transcription units in HeLa nuclei.
od: Jackson, D, i dr.
Izdano: (1998)