Peroxisomal β-oxidation enzyme, DECR2, regulates lipid metabolism and promotes treatment resistance in advanced prostate cancer
Background: Peroxisomes are central metabolic organelles that have key roles in fatty acid homoeostasis. As prostate cancer (PCa) is particularly reliant on fatty acid metabolism, we explored the contribution of peroxisomal β-oxidation (perFAO) to PCa viability and therapy response. Methods: Bioinfo...
Main Authors: | Mah, CY, Nguyen, ADT, Niijima, T, Helm, M, Dehairs, J, Ryan, FJ, Ryan, N, Quek, L, Hoy, AJ, Don, AS, Mills, IG, Swinnen, JV, Lynn, DJ, Nassar, ZD, Butler, LM |
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Format: | Journal article |
Language: | English |
Published: |
Springer Nature [academic journals on nature.com]
2024
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