Role of Syk in B-cell development and antigen-receptor signaling.

Role of Syk in B-cell development and antigen-receptor signaling.

Antigen receptors (BCRs) on developing B lymphocytes play two opposing roles-promoting survival of cells that may later bind a foreign antigen and inhibiting survival of cells that bind too strongly to self-antigens. It is not known how these opposing outcomes are signaled by BCRs on immature B cell...

Disgrifiad llawn

Manylion Llyfryddiaeth
Prif Awduron:	Cornall, R, Cheng, A, Pawson, T, Goodnow, C
Fformat:	Journal article
Iaith:	English
Cyhoeddwyd:	2000

Eitemau Tebyg

B cell antigen receptor signalling in the balance of tolerance and immunity.
gan: Cornall, R, et al.
Cyhoeddwyd: (1998)

Regulation of B cell antigen receptor signaling by the Lyn/CD22/SHP1 pathway.
gan: Cornall, R, et al.
Cyhoeddwyd: (1999)

B cell activation involves nanoscale receptor reorganizations and inside-out signaling by Syk
gan: Kathrin Kläsener, et al.
Cyhoeddwyd: (2014-06-01)

The regulation of self-reactive B cells.
gan: Cornall, R, et al.
Cyhoeddwyd: (1995)

Single epitope multiple staining to detect ultralow frequency B cells.
gan: Townsend, SE, et al.
Cyhoeddwyd: (2001)

Dual Role of the Tyrosine Kinase Syk in Regulation of Toll-Like Receptor Signaling in Plasmacytoid Dendritic Cells.
gan: Besma Aouar, et al.
Cyhoeddwyd: (2016-01-01)

Modulation of BCR Signaling by the Induced Dimerization of Receptor-Associated SYK
gan: Mark L. Westbroek, et al.
Cyhoeddwyd: (2017-12-01)

NDRG1 is induced by antigen-receptor signaling but dispensable for B and T cell self-tolerance
gan: Hodgson, R, et al.
Cyhoeddwyd: (2022)

Swiprosin-1/EFhd2 controls B cell receptor signaling through the assembly of the B cell receptor, Syk, and phospholipase C gamma2 in membrane rafts.
gan: Kroczek, C, et al.
Cyhoeddwyd: (2010)

NDRG1 is induced by antigen-receptor signaling but dispensable for B and T cell self-tolerance
gan: Rose Hodgson, et al.
Cyhoeddwyd: (2022-11-01)

SYK allelic loss and the role of Syk-regulated genes in breast cancer survival.
gan: Jan Blancato, et al.
Cyhoeddwyd: (2014-01-01)

Activation of the Syk tyrosine kinase is insufficient for downstream signal transduction in B lymphocytes
gan: Lee Jamie A, et al.
Cyhoeddwyd: (2002-12-01)

On thermalization in the SYK and supersymmetric SYK models
gan: Nicholas Hunter-Jones, et al.
Cyhoeddwyd: (2018-02-01)

Dual BTK/SYK inhibition with CG-806 (luxeptinib) disrupts B-cell receptor and Bcl-2 signaling networks in mantle cell lymphoma
gan: Elana Thieme, et al.
Cyhoeddwyd: (2022-03-01)

Signals from a self-antigen induce positive selection in early B cell ontogeny but are tolerogenic in adults.
gan: Ferry, H, et al.
Cyhoeddwyd: (2006)

The essential role of DOCK8 in humoral immunity.
gan: Randall, K, et al.
Cyhoeddwyd: (2010)

Reconstruction and signal propagation analysis of the Syk signaling network in breast cancer cells.
gan: Aurélien Naldi, et al.
Cyhoeddwyd: (2017-03-01)

Isotype control of B cell signaling.
gan: Silver, K, et al.
Cyhoeddwyd: (2003)

Immunoglobulin M and D antigen receptors are both capable of mediating B lymphocyte activation, deletion, or anergy after interaction with specific antigen.
gan: Brink, R, et al.
Cyhoeddwyd: (1992)

Monovalent and Multivalent Ligation of the B Cell Receptor Exhibit Differential Dependence upon Syk and Src Family Kinases
gan: Mukherjee, Sayak, et al.
Cyhoeddwyd: (2014)

Analysis of Lyn/CD22 double-deficient B cells in vivo demonstrates Lyn- and CD22-independent pathways affecting BCR regulation and B cell survival (vol 35, pg 3655, 2005)
gan: Ferry, H, et al.
Cyhoeddwyd: (2005)

Analysis of Lyn/CD22 double-deficient B cells in vivo demonstrates Lyn- and CD22-independent pathways affecting BCR regulation and B cell survival.
gan: Ferry, H, et al.
Cyhoeddwyd: (2005)

B cell antigen receptor signaling and internalization are mutually exclusive events.
gan: Ping Hou, et al.
Cyhoeddwyd: (2006-07-01)

Mercury alters endogenous phosphorylation profiles of SYK in murine B cells
gan: Joseph A. Caruso, et al.
Cyhoeddwyd: (2017-07-01)

SYK inhibition thwarts the BAFF - B-cell receptor crosstalk and thereby antagonizes Mcl-1 in chronic lymphocytic leukemia
gan: Cody Paiva, et al.
Cyhoeddwyd: (2017-11-01)

Role of Specific B-Cell Receptor Antigens in Lymphomagenesis
gan: Lorenz Thurner, et al.
Cyhoeddwyd: (2020-12-01)

P1267: HSP110 FAVORS BCR SIGNALING THROUGH SYK PHOSPHORYLATION IN DIFFUSE LARGE B CELL LYMPHOMA
gan: V. Cabaud Gibouin, et al.
Cyhoeddwyd: (2022-06-01)

The role of B cell antigen receptors in mantle cell lymphoma
gan: Michael Fichtner, et al.
Cyhoeddwyd: (2017-10-01)

Involvement of B Cells, Immunoglobulins, and Syk in the Pathogenesis of Abdominal Aortic Aneurysm
gan: Aya Furusho, et al.
Cyhoeddwyd: (2018-03-01)

Seeking to Develop Global SYK-Ness
gan: Dmitri V. Khveshchenko
Cyhoeddwyd: (2018-11-01)

The Role of Molecular Flexibility in Antigen Presentation and T Cell Receptor-Mediated Signaling
gan: Kannan Natarajan, et al.
Cyhoeddwyd: (2018-07-01)

Erratum: Analysis of Lyn/CD22 double-deficient B cells in vivo demonstrates Lyn- and CD22- independent pathways affecting BCR regulation and B cell survival (European Journal of Immunology (2005) vol. 35 (12) (3714) 10.1002/eji.200535247)
gan: Ferry, H, et al.
Cyhoeddwyd: (2005)

Spleen tyrosine kinase (Syk) regulates systemic lupus erythematosus (SLE) T cell signaling.
gan: Alexandros P Grammatikos, et al.
Cyhoeddwyd: (2013-01-01)

A Previously Unknown Unique Challenge for Inhibitors of SYK ATP-Binding Site: Role of SYK as A Cell Cycle Checkpoint Regulator
gan: Fatih M. Uckun, et al.
Cyhoeddwyd: (2014-11-01)

GM-CSF receptor/SYK/JNK/FOXO1/CD11c signaling promotes atherosclerosis
gan: Daisuke Tsukui, et al.
Cyhoeddwyd: (2023-08-01)

Functional role of T-cell receptor nanoclusters in signal initiation and antigen discrimination
gan: Pageon, SV, et al.
Cyhoeddwyd: (2016)

Correction: Syk Signaling in Dendritic Cells Orchestrates Innate Resistance to Systemic Fungal Infection.
gan: Paul G Whitney, et al.
Cyhoeddwyd: (2018-11-01)

Source data for: Hodgson et al, NDRG1 is induced by antigen-receptor signaling but dispensable for B and T cell self-tolerance, Communications Biology 2022
gan: Hodgson, R, et al.
Cyhoeddwyd: (2022)

Signaling Response to Transient Redox Stress in Human Isolated T Cells: Molecular Sensor Role of Syk Kinase and Functional Involvement of IL2 Receptor and L-Selectine
gan: Christian Secchi, et al.
Cyhoeddwyd: (2020-01-01)

Vector models and generalized SYK models
gan: Cheng Peng
Cyhoeddwyd: (2017-05-01)