Mass spectrometry of RNA.
A complex population of non-coding RNAs is present in higher organisms. These RNAs have a multitude of functions and execute control over gene expression through various, often poorly understood, mechanisms. At present, the identification and analysis of functional regulatory RNAs and disparate ribo...
Main Authors: | , |
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Format: | Journal article |
Language: | English |
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2006
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_version_ | 1797074043856224256 |
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author | Thomas, B Akoulitchev, A |
author_facet | Thomas, B Akoulitchev, A |
author_sort | Thomas, B |
collection | OXFORD |
description | A complex population of non-coding RNAs is present in higher organisms. These RNAs have a multitude of functions and execute control over gene expression through various, often poorly understood, mechanisms. At present, the identification and analysis of functional regulatory RNAs and disparate ribonucleoprotein complexes remain an experimental challenge for biologists. They require specially designed approaches and techniques in genomics and RNA biochemistry. Developments in technologies based on mass spectrometry could offer sensitive and efficient solutions to analysis of the sequence, structure, modification and composition of RNA. |
first_indexed | 2024-03-06T23:30:40Z |
format | Journal article |
id | oxford-uuid:6be8fa38-41cf-4af8-92df-92991310b397 |
institution | University of Oxford |
language | English |
last_indexed | 2024-03-06T23:30:40Z |
publishDate | 2006 |
record_format | dspace |
spelling | oxford-uuid:6be8fa38-41cf-4af8-92df-92991310b3972022-03-26T19:07:18ZMass spectrometry of RNA.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:6be8fa38-41cf-4af8-92df-92991310b397EnglishSymplectic Elements at Oxford2006Thomas, BAkoulitchev, AA complex population of non-coding RNAs is present in higher organisms. These RNAs have a multitude of functions and execute control over gene expression through various, often poorly understood, mechanisms. At present, the identification and analysis of functional regulatory RNAs and disparate ribonucleoprotein complexes remain an experimental challenge for biologists. They require specially designed approaches and techniques in genomics and RNA biochemistry. Developments in technologies based on mass spectrometry could offer sensitive and efficient solutions to analysis of the sequence, structure, modification and composition of RNA. |
spellingShingle | Thomas, B Akoulitchev, A Mass spectrometry of RNA. |
title | Mass spectrometry of RNA. |
title_full | Mass spectrometry of RNA. |
title_fullStr | Mass spectrometry of RNA. |
title_full_unstemmed | Mass spectrometry of RNA. |
title_short | Mass spectrometry of RNA. |
title_sort | mass spectrometry of rna |
work_keys_str_mv | AT thomasb massspectrometryofrna AT akoulitcheva massspectrometryofrna |