Developing viral vectored vaccines for MAGE-expressing tumours
The MAGE-type antigen family represent excellent targets for a therapeutic cancer vaccine. However, numerous attempts to develop effective MAGE-targeting cancer vaccines to date have shown poor induction of specific CD8+ T-cell responses and little clinical efficacy. In this study, a novel vaccinati...
Main Author: | McAuliffe, J |
---|---|
Other Authors: | Leung, C |
Format: | Thesis |
Language: | English |
Published: |
2020
|
Subjects: |
Similar Items
-
Harnessing the immune system to reject cancers through genetic modifications of tumour cells
by: Ajzensztejn, D
Published: (2015) -
Targeting the hypoxic tumour phenotype with T-cell immunotherapy
by: Chong, T
Published: (2004) -
The role of tryptophan and the mTOR pathway in T cell fate determination
by: Karydis, I, et al.
Published: (2014) -
Remodelling of the immune landscape and its effect of tumour immunity in a model of IFNy-insensitive murine melanoma
by: Lau, VWC
Published: (2023) -
Investigating checkpoint inhibitor-induced gastrointestinal disease: comparisons with idiopathic ulcerative colitis and health
by: Gupta, T
Published: (2022)