Mutations in the linker domain of NBD2 of SUR inhibit transduction but not nucleotide binding.

ATP-sensitive potassium (K(ATP)) channels are composed of an ATP-binding cassette (ABC) protein (SUR1, SUR2A or SUR2B) and an inwardly rectifying K(+) channel (Kir6.1 or Kir6.2). Like other ABC proteins, the nucleotide binding domains (NBDs) of SUR contain a highly conserved "signature sequence...

Полное описание

Библиографические подробности
Главные авторы: Matsuo, M, Dabrowski, M, Ueda, K, Ashcroft, F
Формат: Journal article
Язык:English
Опубликовано: 2002