Cerebral calpain in fatal falciparum malaria.

Disruption of axonal transport may represent a final common pathway leading to neurological dysfunction in cerebral malaria (CM). Calpains are calcium (Ca2+)-activated cysteine proteases which have been implicated in axonal injury in neurological diseases of various aetiologies. In this study we exa...

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Bibliographic Details
Main Authors: Medana, I, Day, N, Hien, T, Mai, N, Bethell, D, Phu, N, Turner, G, Farrar, J, White, N, Esiri, M
Format: Journal article
Language:English
Published: 2007