Molecular architecture and ligand recognition determinants for T4 RNA ligase.
RNA ligase type 1 from bacteriophage T4 (Rnl1) is involved in countering a host defense mechanism by repairing 5'-PO4 and 3'-OH groups in tRNA(Lys). Rnl1 is widely used as a reagent in molecular biology. Although many structures for DNA ligases are available, only fragments of RNA ligases...
Main Authors: | El Omari, K, Ren, J, Bird, L, Bona, M, Klarmann, G, LeGrice, S, Stammers, D |
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Format: | Journal article |
Language: | English |
Published: |
2006
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