Adenovirus-mediated GTP cyclohydrolase I gene delivery augments tetrahydrobiopterin and restores nitric oxide synthase function in hyperglycaemic human aortic endothelial cells

Adenovirus-mediated GTP cyclohydrolase I gene delivery augments tetrahydrobiopterin and restores nitric oxide synthase function in hyperglycaemic human aortic endothelial cells

Бусад хувилбаруудыг харуулах (1)

Номзүйн дэлгэрэнгүй
Үндсэн зохиолчид:	Cai, S, Channon, K
Формат:	Conference item
Хэвлэсэн:	2004

Ижил төстэй зүйлс

Adenovirus-mediated GTP cyclohydrolase I gene delivery augments tetrahydrobiopterin and restores nitric oxide synthase function in hyperglycaemic human aortic endothelial cells
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GTP cyclohydrolase I gene transfer augments intracellular tetrahydrobiopterin in human endothelial cells: effects on nitric oxide synthase activity, protein levels and dimerisation.
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Nitric oxide Bioavailability is preserved in diabetes by increased endothelial tetrahydrobiopterin synthesis in targeted GTP cyclohydrolase transgenic mice
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Systemic adenovirus-mediated gene transfer of human GTP cyclohydrolase-1 increases liver, plasma and aortic tetrahydrobiopterin levels in mice
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Tetrahydrobiopterin-dependent preservation of nitric oxide-mediated endothelial function in diabetes by targeted transgenic GTP-cyclohydrolase I overexpression.
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Cell-autonomous role of endothelial GTP cyclohydrolase 1 and tetrahydrobiopterin in blood pressure regulation.
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Cell-autonomous role of endothelial GTP cyclohydrolase 1 and tetrahydrobiopterin in blood pressure regulation
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Tetrahydrobiopterin-dependent preservation of nitric oxide-mediated endothelial function in diabetes by targeted transgenic GTP-cyclohydrolase I over-expression
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GTP cyclohydrolase I expression, protein, and activity determine intracellular tetrahydrobiopterin levels, independent of GTP cyclohydrolase feedback regulatory protein expression.
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Nitric oxide bioactivity in ApoE -/- mice is maintained by increased endothelial tetrahydrobiopterin synthesis via targeted GTP cyclohydrolase-1 over-expression
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Quantitative regulation of intracellular endothelial nitric-oxide synthase (eNOS) coupling by both tetrahydrobiopterin-eNOS stoichiometry and biopterin redox status: insights from cells with tet-regulated GTP cyclohydrolase I expression.
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cGMP Inhibits GTP Cyclohydrolase I Activity and Biosynthesis of Tetrahydrobiopterin in Human Umbilical Vein Endothelial Cells
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Statin Increases GTP Cyclohydrolase I mRNA and 5,6,7,8-Tetrahydrobiopterin in Vascular Endothelial Cells
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