Validating the RedMIT/GFP-LC3 mouse model by studying mitophagy in autosomal dominant optic atrophy due to the OPA1Q285STOP mutation

<h4>Background</h4> <p>Autosomal dominant optic atrophy (ADOA) is usually caused by mutations in the essential gene, OPA1. This encodes a ubiquitous protein involved in mitochondrial dynamics, hence tissue specificity is not understood. Dysregulated mitophagy (mitochondria recycli...

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Podrobná bibliografie
Hlavní autoři:	Diot, A, Agnew, T, Sanderson, J, Liao, C, Carver, J, Neves, R, Gupta, R, Guo, Y, Waters, C, Seto, S, Daniels, M, Dombi, E, Lodge, T, Morten, K, Williams, S, Enver, T, Iborra, F, Votruba, M, Poulton, J
Médium:	Journal article
Jazyk:	English
Vydáno:	Frontiers Media 2018

Validating the RedMIT/GFP-LC3 mouse model by studying mitophagy in autosomal dominant optic atrophy due to the OPA1Q285STOP mutation

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