Polymeric microellipsoids with programmed magnetic anisotropy for controlled rotation using low (≈10 mT) magnetic fields
Polymeric magnetic spherical microparticles are employed as sensors/actuators in lab-on-a-chip applications, small-scale robotics and biomedical/biophysical assays. Achieving controlled stable motion of the microparticles in a fluid environment using low intensity magnetic fields is necessary to ach...
| Main Authors: | , , , , , , , |
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| Format: | Journal article |
| Language: | English |
| Published: |
Elsevier
2019
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| _version_ | 1826277703330824192 |
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| author | Bonilla Brunner, A Llorente Garcia, I Jang, B Amano Patino, M Alimchandani, V Nelson, B Pane, S Antoranz Contera, S |
| author_facet | Bonilla Brunner, A Llorente Garcia, I Jang, B Amano Patino, M Alimchandani, V Nelson, B Pane, S Antoranz Contera, S |
| author_sort | Bonilla Brunner, A |
| collection | OXFORD |
| description | Polymeric magnetic spherical microparticles are employed as sensors/actuators in lab-on-a-chip applications, small-scale robotics and biomedical/biophysical assays. Achieving controlled stable motion of the microparticles in a fluid environment using low intensity magnetic fields is necessary to achieve much of their technological potential; this requires that the microparticle is magnetically anisotropic, which is difficult to achieve in spheres. Here we have developed a simple method to synthesise anisotropic ellipsoidal microparticles (average eccentricity 0.60 ± 0.14) by applying a magnetic field during synthesis, using a nanocomposite of polycaprolactone (PCL) with Fe3O4 nanowires. The “microellipsoids” are thoroughly characterised using optical microscopy, scanning electron microscopy (SEM), transmission electron microscopy (TEM) and energy dispersive X-ray spectroscopy (EDX). Their suitability for magnetically controlled motion is demonstrated by analysing their rotation in low magnetic fields (0.1, 1, 5, 10 and 20 mT) at varying rotational frequencies (1 Hz and 5 Hz). The microellipsoids are able to follow smoothly and continuously the magnetic field, while commercial spherical particles fail to continuously follow the magnetic field, and oscillate backwards and forwards resulting in much lower average angular speeds. Furthermore, only 23 % of commercial particles analysed rotated at 1 Hz and 26 % at 5 Hz, whereas 77 % of our ellipsoidal particles rotated at 1 Hz, and 74 % did at 5 Hz. |
| first_indexed | 2024-03-06T23:32:55Z |
| format | Journal article |
| id | oxford-uuid:6cab95af-60bc-4a34-a87e-7b3ec88a0dbc |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-06T23:32:55Z |
| publishDate | 2019 |
| publisher | Elsevier |
| record_format | dspace |
| spelling | oxford-uuid:6cab95af-60bc-4a34-a87e-7b3ec88a0dbc2022-03-26T19:12:34ZPolymeric microellipsoids with programmed magnetic anisotropy for controlled rotation using low (≈10 mT) magnetic fieldsJournal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:6cab95af-60bc-4a34-a87e-7b3ec88a0dbcEnglishSymplectic Elements at OxfordElsevier2019Bonilla Brunner, ALlorente Garcia, IJang, BAmano Patino, MAlimchandani, VNelson, BPane, SAntoranz Contera, SPolymeric magnetic spherical microparticles are employed as sensors/actuators in lab-on-a-chip applications, small-scale robotics and biomedical/biophysical assays. Achieving controlled stable motion of the microparticles in a fluid environment using low intensity magnetic fields is necessary to achieve much of their technological potential; this requires that the microparticle is magnetically anisotropic, which is difficult to achieve in spheres. Here we have developed a simple method to synthesise anisotropic ellipsoidal microparticles (average eccentricity 0.60 ± 0.14) by applying a magnetic field during synthesis, using a nanocomposite of polycaprolactone (PCL) with Fe3O4 nanowires. The “microellipsoids” are thoroughly characterised using optical microscopy, scanning electron microscopy (SEM), transmission electron microscopy (TEM) and energy dispersive X-ray spectroscopy (EDX). Their suitability for magnetically controlled motion is demonstrated by analysing their rotation in low magnetic fields (0.1, 1, 5, 10 and 20 mT) at varying rotational frequencies (1 Hz and 5 Hz). The microellipsoids are able to follow smoothly and continuously the magnetic field, while commercial spherical particles fail to continuously follow the magnetic field, and oscillate backwards and forwards resulting in much lower average angular speeds. Furthermore, only 23 % of commercial particles analysed rotated at 1 Hz and 26 % at 5 Hz, whereas 77 % of our ellipsoidal particles rotated at 1 Hz, and 74 % did at 5 Hz. |
| spellingShingle | Bonilla Brunner, A Llorente Garcia, I Jang, B Amano Patino, M Alimchandani, V Nelson, B Pane, S Antoranz Contera, S Polymeric microellipsoids with programmed magnetic anisotropy for controlled rotation using low (≈10 mT) magnetic fields |
| title | Polymeric microellipsoids with programmed magnetic anisotropy for controlled rotation using low (≈10 mT) magnetic fields |
| title_full | Polymeric microellipsoids with programmed magnetic anisotropy for controlled rotation using low (≈10 mT) magnetic fields |
| title_fullStr | Polymeric microellipsoids with programmed magnetic anisotropy for controlled rotation using low (≈10 mT) magnetic fields |
| title_full_unstemmed | Polymeric microellipsoids with programmed magnetic anisotropy for controlled rotation using low (≈10 mT) magnetic fields |
| title_short | Polymeric microellipsoids with programmed magnetic anisotropy for controlled rotation using low (≈10 mT) magnetic fields |
| title_sort | polymeric microellipsoids with programmed magnetic anisotropy for controlled rotation using low ≈10 mt magnetic fields |
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