Gene x gene interactions in genome wide association studies

Gene x gene interactions in genome wide association studies

<p>Genome wide association studies (GWAS) have revolutionized our approach to mapping genetic determinants of complex human diseases. However, even with success from recent studies, we have typically been able to explain only a fraction of the trait heritability. GWAS are typically analysed by...

وصف كامل

التفاصيل البيبلوغرافية
المؤلف الرئيسي:	Bhattacharya, K
مؤلفون آخرون:	Morris, A
التنسيق:	أطروحة
اللغة:	English
منشور في:	2014
الموضوعات:	Statistics (see also social sciences) Bioinformatics (technology) Bioinformatics (life sciences) Mathematical genetics and bioinformatics (statistics) Mathematical biology Genetics (life sciences) Mathematics

مواد مشابهة

Extensions of the case-control design in genome-wide association studies
حسب: Loizides, C
منشور في: (2012)

Using phylogeny to improve genome-wide distant homology recognition
حسب: Abeln, S, وآخرون
منشور في: (2007)

Quantifying the underestimation of relative risks from genome-wide association studies
حسب: Spencer, C, وآخرون
منشور في: (2011)

Protein protein interactions, evolutionary rate, abundance and age
حسب: Saeed, R, وآخرون
منشور في: (2006)

Cotranslational protein folding - fact or fiction?
حسب: Deane, C, وآخرون
منشور في: (2007)

Modelling sequential protein folding under kinetic control
حسب: Huard, F, وآخرون
منشور في: (2006)

A statistical approach using network structure in the prediction of protein characteristics
حسب: Chen, P, وآخرون
منشور في: (2007)

Multilocus approaches to the detection of disease susceptibility regions: methods and applications
حسب: Ciampa, J
منشور في: (2012)

Statistical HLA type imputation from large and heterogeneous datasets
حسب: Dilthey, A
منشور في: (2012)

Rahnuma: hypergraph-based tool for metabolic pathway prediction and network comparison
حسب: Mithani, A, وآخرون
منشور في: (2009)

Increasing statistical power and generalizability in genomics microarray research
حسب: Ramasamy, A
منشور في: (2009)

HLA*IMP - an integrated framework for imputing classical HLA alleles from SNP genotypes
حسب: Dilthey, A, وآخرون
منشور في: (2011)

Bayesian methods for multivariate phenotype analysis in genome-wide association studies
حسب: Iotchkova, V
منشور في: (2013)

Design and analysis of genome-wide association studies
حسب: Barrett, J
منشور في: (2008)

An integrated genomic approach for the identification and analysis of single nucleotide polymorphisms that affect cancer in humans
حسب: Repapi, E
منشور في: (2013)

Bayesian methods for estimating human ancestry using whole genome SNP data
حسب: Churchhouse, C
منشور في: (2012)

The estimation of recombination rates from population genetic data
حسب: Auton, A
منشور في: (2007)

Statistical challenges in the detection of mutation and variation using high throughput sequencing
حسب: Pfeifer, S
منشور في: (2012)

Statistical and Computational Methodology for the Analysis of Forensic DNA Mixtures with Artefacts
حسب: Graversen, T
منشور في: (2014)

Exploring the fold space preferences of ancient and newborn protein superfamilies
حسب: Edwards, H, وآخرون
منشور في: (2014)

Application of the Neutral Indel Model to genome sequences for diverse metazoans
حسب: Meader, S
منشور في: (2010)

Protein loop structure prediction
حسب: Choi, Y
منشور في: (2011)

Large-scale genetic analysis of quantitative traits
حسب: Randall, J, وآخرون
منشور في: (2012)

A method for the identification of biological pathways
حسب: Honti, F
منشور في: (2014)

On genetic variants underlying common disease
حسب: Hechter, E
منشور في: (2011)

Bayesian and frequentist methods and analyses of genome-wide association studies
حسب: Vukcevic, D
منشور في: (2009)

Selection along the HIV-1 genome through the CTL mediated immune response
حسب: Palmer, D
منشور في: (2014)

Imputation aided analysis of the association between autoimmune diseases and the MHC
حسب: Moutsianas, L
منشور في: (2011)

Inferring the fine-scale structure and evolution of recombination from high-throughput genome sequencing
حسب: Venn, O
منشور في: (2013)

The evolutionary dynamics of neutral networks: lessons from RNA
حسب: Rendel, M
منشور في: (2008)

Genome-wide DNaseI hypersensitive sites profiles in laboratory mouse strains by DNase-seq
حسب: Hosseini, M
منشور في: (2013)

Protein fold evolution on completed genomes: distinguishing between young and old folds
حسب: Abeln, S, وآخرون
منشور في: (2007)

Genome annotation and selectional analysis of viral evolution
حسب: de Groot, S
منشور في: (2008)

Fold recognition and alignment in the ‘twilight zone’
حسب: Hill, J, وآخرون
منشور في: (2013)

Statistical methods for the analysis of genetic association studies
حسب: Su, Z
منشور في: (2008)

Bayesian methods for fine mapping in genetic association studies
حسب: Frangou, E
منشور في: (2013)

Genes contributing to variation in fear-related behaviour
حسب: Krohn, J, وآخرون
منشور في: (2013)

A robust clustering algorithm for identifying problematic samples in genome-wide association studies
حسب: Bellenguez, C, وآخرون
منشور في: (2012)

Statistical models for single-cell data
حسب: Pierson, E
منشور في: (2015)

A flexible and accurate genotype imputation method for the next generation of genome-wide association studies
حسب: Howie, B, وآخرون
منشور في: (2009)