C2028T polymorphism in exon 12 and dinucleotide repeat polymorphism in intron 13 of the HIF-1alpha gene define HIF-1alpha protein expression in non-small cell lung cancer.

OBJECTIVES: In this study, we investigated whether polymorphisms of the HIF-1alpha gene may account for the patterns of HIF-1alpha protein expression in non-small cell lung carcinomas (NSCLC) and the expression of HIF-1alpha down-stream proteins. METHODS: Specific HIF-1alpha polymorphisms were asse...

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Bibliographic Details
Main Authors: Koukourakis, M, Papazoglou, D, Giatromanolaki, A, Panagopoulos, I, Maltezos, E, Harris, A, Gatter, K, Sivridis, E
Format: Journal article
Language:English
Published: 2006