The clinical use of memantine
This review outlines the use of memantine in clinical practice and represents the output of a consensus group who met to consider the use of the drug. The main conclusions were: memantine, a glutamatergic agent, has a different mode of action to the other available agents, for the treatment of Alzhe...
| Principais autores: | , , , , , , , , , , , , , |
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| Formato: | Journal article |
| Idioma: | English |
| Publicado em: |
2005
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| _version_ | 1826277800265383936 |
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| author | Burns, A Ballard, C Banerjee, S Calabrese, P De Deyn, P Grossberg, G Jones, R Sandman, P Selmes, J Vellas, B Waldemar, G Wilcock, G Winblad, B Zaudig, M |
| author_facet | Burns, A Ballard, C Banerjee, S Calabrese, P De Deyn, P Grossberg, G Jones, R Sandman, P Selmes, J Vellas, B Waldemar, G Wilcock, G Winblad, B Zaudig, M |
| author_sort | Burns, A |
| collection | OXFORD |
| description | This review outlines the use of memantine in clinical practice and represents the output of a consensus group who met to consider the use of the drug. The main conclusions were: memantine, a glutamatergic agent, has a different mode of action to the other available agents, for the treatment of Alzheimer's disease, the anticholinesterases; is indicated for the treatment of moderately severe to severe Alzheimer's disease; shows efficacy over placebo in improving cognitive function, activities of daily living and global assessments; is well tolerated with a favourable side effect profile (the main side effects are hallucinations, confusion, dizziness, headache and tiredness) and; can be combined with good efficacy and safety with donepezil. Memantine looks likely to prove a valuable new tool in clinical practice. |
| first_indexed | 2024-03-06T23:34:21Z |
| format | Journal article |
| id | oxford-uuid:6d226f0f-8c5d-4b05-a052-b61a703e7d37 |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-06T23:34:21Z |
| publishDate | 2005 |
| record_format | dspace |
| spelling | oxford-uuid:6d226f0f-8c5d-4b05-a052-b61a703e7d372022-03-26T19:15:54ZThe clinical use of memantineJournal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:6d226f0f-8c5d-4b05-a052-b61a703e7d37EnglishSymplectic Elements at Oxford2005Burns, ABallard, CBanerjee, SCalabrese, PDe Deyn, PGrossberg, GJones, RSandman, PSelmes, JVellas, BWaldemar, GWilcock, GWinblad, BZaudig, MThis review outlines the use of memantine in clinical practice and represents the output of a consensus group who met to consider the use of the drug. The main conclusions were: memantine, a glutamatergic agent, has a different mode of action to the other available agents, for the treatment of Alzheimer's disease, the anticholinesterases; is indicated for the treatment of moderately severe to severe Alzheimer's disease; shows efficacy over placebo in improving cognitive function, activities of daily living and global assessments; is well tolerated with a favourable side effect profile (the main side effects are hallucinations, confusion, dizziness, headache and tiredness) and; can be combined with good efficacy and safety with donepezil. Memantine looks likely to prove a valuable new tool in clinical practice. |
| spellingShingle | Burns, A Ballard, C Banerjee, S Calabrese, P De Deyn, P Grossberg, G Jones, R Sandman, P Selmes, J Vellas, B Waldemar, G Wilcock, G Winblad, B Zaudig, M The clinical use of memantine |
| title | The clinical use of memantine |
| title_full | The clinical use of memantine |
| title_fullStr | The clinical use of memantine |
| title_full_unstemmed | The clinical use of memantine |
| title_short | The clinical use of memantine |
| title_sort | clinical use of memantine |
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