Transmission of HIV-1 Gag immune escape mutations is associated with reduced viral load in linked recipients.

Transmission of HIV-1 Gag immune escape mutations is associated with reduced viral load in linked recipients.

In a study of 114 epidemiologically linked Zambian transmission pairs, we evaluated the impact of human leukocyte antigen class I (HLA-I)-associated amino acid polymorphisms, presumed to reflect cytotoxic T lymphocyte (CTL) escape in Gag and Nef of the virus transmitted from the chronically infected...

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Bibliographic Details
Main Authors:	Goepfert, P, Lumm, W, Farmer, P, Matthews, P, Prendergast, A, Carlson, J, Derdeyn, C, Tang, J, Kaslow, R, Bansal, A, Yusim, K, Heckerman, D, Mulenga, J, Allen, S, Goulder, P, Hunter, E
Format:	Journal article
Language:	English
Published:	2008

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