Selective binding of AIRAPL tandem UIMs to lys48-linked tri-ubiquitin chains
<p>Lys48-linked ubiquitin chains act as the main targeting signals for protein degradation by the proteasome. Here we report selective binding of AIRAPL, a protein that associates with the proteasome upon exposure to arsenite, to Lys48-linked tri-ubiquitin chains. AIRAPL comprises two ubiquiti...
| Hlavní autoři: | , , , , , , , , , |
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| Médium: | Journal article |
| Vydáno: |
Cell Press
2016
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