Irbesartan lowers superoxide levels and increases nitric oxide bioavailability in blood vessels from spontaneously hypertensive stroke-prone rats.

Irbesartan lowers superoxide levels and increases nitric oxide bioavailability in blood vessels from spontaneously hypertensive stroke-prone rats.

OBJECTIVE: To determine the effects of the angiotensin II receptor antagonist irbesartan, the calcium-channel blocker amlodipine, and hydrochlorothiazide/hydralazine on superoxide, NAD(P)H oxidase and nitric oxide bioavailability in spontaneously hypertensive stroke-prone rats (SHRSP). METHODS: Dru...

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Bibliographic Details
Main Authors:	Brosnan, M, Hamilton, C, Graham, D, Lygate, C, Jardine, E, Dominiczak, A
Format:	Journal article
Language:	English
Published:	2002

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