Mepolizumab for eosinophilic chronic obstructive pulmonary disease

Mepolizumab for eosinophilic chronic obstructive pulmonary disease

Patients with chronic obstructive pulmonary disease (COPD) with an eosinophilic phenotype may benefit from treatment with mepolizumab, a monoclonal antibody directed against interleukin-5.We performed two phase 3, randomized, placebo-controlled, double-blind, parallel-group trials comparing mepolizu...

पूर्ण विवरण

ग्रंथसूची विवरण
मुख्य लेखकों:	Pavord, I, Chanez, P, Criner, G, Kerstjens, H, Korn, S, Lugogo, N, Martinot, J, Sagara, H, Albers, F, Bradford, E, Harris, S, Mayer, B, Rubin, D, Yancey, S, Sciurba, F
स्वरूप:	Journal article
भाषा:	English
प्रकाशित:	Massachusetts Medical Society 2017

समान संसाधन

Late breaking abstract - Dose-ranging study of mepolizumab in eosinophilic COPD
द्वारा: Pavord, I, और अन्य
प्रकाशित: (2017)

Mepolizumab for Eosinophilic Chronic Obstructive Pulmonary Disease (COPD): A Meta-Analysis of METREX and METREO Exacerbation Endpoints
द्वारा: Bafadhel, M, और अन्य
प्रकाशित: (2018)

Mepolizumab for eosinophilic COPD
द्वारा: Sciurba, F, और अन्य
प्रकाशित: (2018)

Mepolizumab for Eosinophilic Chronic Obstructive Pulmonary Disease (COPD): A Meta-Analysis of METREX and METREO Patient-Reported Outcomes, Response to Therapy and Lung Function
द्वारा: Chapman, K, और अन्य
प्रकाशित: (2018)

Evaluation of potential continuation rules for mepolizumab treatment of severe eosinophilic asthma.
द्वारा: Gunsoy, N, और अन्य
प्रकाशित: (2017)

Mepolizumab treatment in patients with severe eosinophilic asthma.
द्वारा: Ortega, H, और अन्य
प्रकाशित: (2014)

Glucocorticoids and mepolizumab in eosinophilic asthma.
द्वारा: Bel, E, और अन्य
प्रकाशित: (2014)

Fractional exhaled nitric oxide and the peripheral blood eosinophil count as biomarkers of the response to mepolizumab in patients with severe eosinophilic asthma
द्वारा: Shrimanker, R, और अन्य
प्रकाशित: (2018)

Mepolizumab in the treatment of eosinophilic chronic obstructive pulmonary disease
द्वारा: Mkorombindo T, और अन्य
प्रकाशित: (2019-08-01)

Mepolizumab for severe eosinophilic asthma (DREAM): a multicentre, double-blind, placebo-controlled trial.
द्वारा: Pavord, I, और अन्य
प्रकाशित: (2012)

Oral glucocorticoid-sparing effect of mepolizumab in eosinophilic asthma.
द्वारा: Bel, E, और अन्य
प्रकाशित: (2014)

Efficacy of add-on mepolizumab in adolescents with severe eosinophilic asthma
द्वारा: Steven W. Yancey, और अन्य
प्रकाशित: (2019-09-01)

Severe eosinophilic asthma treated with mepolizumab stratified by baseline eosinophil thresholds: a secondary analysis of the DREAM and MENSA studies.
द्वारा: Ortega, H, और अन्य
प्रकाशित: (2016)

Meta-analysis of asthma-related hospitalization in mepolizumab studies of severe eosinophilic asthma
द्वारा: Yancey, S, और अन्य
प्रकाशित: (2016)

Mepolizumab in refractory eosinophilic asthma.
द्वारा: Pavord, I, और अन्य
प्रकाशित: (2010)

Mepolizumab, quality of life, and severe eosinophilic asthma.
द्वारा: Pavord, I
प्रकाशित: (2017)

Clinical characterisation of exacerbations of severe eosinophilic asthma occurring on mepolizumab and placebo
द्वारा: Howell, I, और अन्य
प्रकाशित: (2024)

Response to Mepolizumab Treatment in Patients with Severe Eosinophilic Asthma and Atopic Phenotypes
द्वारा: Prazma CM, और अन्य
प्रकाशित: (2021-06-01)

Evaluation of sputum eosinophil count as a predictor of treatment response to mepolizumab
द्वारा: Ian D. Pavord, और अन्य
प्रकाशित: (2022-05-01)

Clinical characterisation of exacerbations of severe eosinophilic asthma occurring on mepolizumab and placebo
द्वारा: Imran Howell, और अन्य
प्रकाशित: (2024-07-01)

Efficacy and safety of mepolizumab in Japanese patients with severe eosinophilic asthma
द्वारा: Terufumi Shimoda, और अन्य
प्रकाशित: (2017-07-01)

Mepolizumab or placebo for eosinophilic granulomatosis with polyangiitis
द्वारा: Wechsler, M, और अन्य
प्रकाशित: (2017)

Blood eosinophil depletion with mepolizumab, benralizumab and prednisolone in eosinophilic asthma
द्वारा: Moran, AM, और अन्य
प्रकाशित: (2020)

Mepolizumab and exacerbations of refractory eosinophilic asthma.
द्वारा: Haldar, P, और अन्य
प्रकाशित: (2009)

Response to mepolizumab treatment is sustained across 4-weekly dosing periods
द्वारा: Ian D. Pavord, और अन्य
प्रकाशित: (2020-09-01)

Efficacy and safety of mepolizumab in Korean patients with severe eosinophilic asthma from the DREAM and MENSA studies
द्वारा: Mi-Kyeong Kim, और अन्य
प्रकाशित: (2021-03-01)

Mepolizumab reduces exacerbations in patients with severe eosinophilic asthma, irrespective of body weight/body mass index: meta-analysis of MENSA and MUSCA
द्वारा: Frank C. Albers, और अन्य
प्रकाशित: (2019-07-01)

Treatment of eosinophilic myositis with mepolizumab
द्वारा: Saadia Waheed, और अन्य
प्रकाशित: (2018-01-01)

GLUCOLD, eosinophils and chronic obstructive pulmonary disease
द्वारा: Pavord, I
प्रकाशित: (2018)

Mepolizumab and the response to oral prednisolone in patients with severe eosinophilic asthma
द्वारा: Shrimanker, R, और अन्य
प्रकाशित: (2017)

Biomarkers for severe eosinophilic asthma.
द्वारा: Yancey, S, और अन्य
प्रकाशित: (2017)

Clinical usefulness of mepolizumab in severe eosinophilic asthma
द्वारा: Menzella F, और अन्य
प्रकाशित: (2016-06-01)

Characterisation of exacerbations of severe eosinophilic asthma (SEA) on mepolizumab compared to placebo
द्वारा: Shrimanker, R, और अन्य
प्रकाशित: (2017)

Depletion rate of blood eosinophils with mepolizumab, benralizumab and oral prednisolone in patients with severe asthma
द्वारा: Moran, A, और अन्य
प्रकाशित: (2020)

Clinical Benefit of Mepolizumab in Eosinophilic Granulomatosis With Polyangiitis for Patients With and Without a Vasculitic Phenotype
द्वारा: Benjamin Terrier, और अन्य
प्रकाशित: (2023-07-01)

Blood eosinophil phenotype during treatment with mepolizumab in patients with severe eosinophilic asthma
द्वारा: Chio Sakai, और अन्य
प्रकाशित: (2024-07-01)

Mepolizumab-responsive recurrent eosinophilic eruption without peripheral eosinophilia
द्वारा: Nina B. Curkovic, MD, और अन्य
प्रकाशित: (2024-11-01)

Safety and Efficacy of Mepolizumab in Patients with Eosinophilic Granulomatosis with Polyangiitis
द्वारा: Ravi Ranjan Pradhan, और अन्य
प्रकाशित: (2019-01-01)

Effectiveness of mepolizumab for eosinophilic pneumonia following bronchial thermoplasty
द्वारा: Ryota Otoshi, और अन्य
प्रकाशित: (2020-03-01)

Remission outcomes in severe eosinophilic asthma with mepolizumab therapy: Analysis of the REDES study
द्वारा: Ian Pavord, और अन्य
प्रकाशित: (2023-04-01)