ST2 regulates allergic airway inflammation and T-cell polarization in epicutaneously sensitized mice.

ST2 regulates allergic airway inflammation and T-cell polarization in epicutaneously sensitized mice.

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IL-33 is an inducer of proinflammatory and T-helper type 2 (Th2) cytokines, which have an important role in atopic dermatitis (AD) and allergic asthma. ST2 is a specific receptor for IL-33 and is expressed on Th2 cells, eosinophils and mast cells. A murine model of AD was used to characterize the ro...

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Main Authors:	Savinko, T, Karisola, P, Lehtimäki, S, Lappeteläinen, A, Haapakoski, R, Wolff, H, Lauerma, A, Alenius, H
格式:	Journal article
语言:	English
出版:	2013

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