Catalytic enantioselective synthesis of indanes by a cation-directed 5-endo-trig cyclization
5-Endo-trig cyclizations are generally considered to be kinetically unfavourable, as described by Baldwin's rules. Consequently, observation of this mode of reaction under kinetic control is rare. This is usually ascribed to challenges in achieving appropriate approach trajectories for orbital...
Main Authors: | Johnston, C, Kothari, A, Sergeieva, T, Okovytyy, S, Jackson, K, Paton, R, Smith, M |
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Format: | Journal article |
Language: | English |
Published: |
Nature Publishing Group
2015
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