Synthesis and O-phosphorylation of 3,3,4,4-tetrafluoroaryl-C-nucleoside analogues
Enantioenriched tetrafluorinated aryl-C-nucleosides were synthesised in four steps from 1-benzyloxy-4-bromo-3,3,4,4-tetrafluorobutan-2-ol. The presence of the tetrafluorinated ethylene group is compatible with O-phosphorylation of the primary alcohol, as demonstrated by the successful preparation of...
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Bibliographic Details
| Main Authors: |
Bonnac, L,
Lee, SE,
Giuffredi, G,
Elphick, L,
Anderson, A,
Child, E,
Mann, D,
Gouverneur, V |
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| Format: | Journal article
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| Language: | English |
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| Published: |
2010
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