Vaccinia virus serpins B13R and B22R do not inhibit antigen presentation to class I-restricted cytotoxic T lymphocytes.

Vaccinia virus serpins B13R and B22R do not inhibit antigen presentation to class I-restricted cytotoxic T lymphocytes.

Vaccinia virus (VV) inhibits the presentation of certain epitopes from influenza virus nucleoprotein (NP), haemagglutinin (HA) and non-structural 1 (NS1) proteins to CD8+ cytotoxic T lymphocytes (CTL) by an unknown mechanism. We have investigated whether VV genes B13R and B22R, which encode proteins...

Full description

Bibliographic Details
Main Authors:	Blake, N, Kettle, S, Law, K, Gould, K, Bastin, J, Townsend, A, Smith, G
Format:	Journal article
Language:	English
Published:	1995

Similar Items

DO VACCINIA VIRUS-ENCODED SERPINS INHIBIT ANTIGEN PRESENTATION TO CLASS I-RESTRICTED CTL
by: Blake, N, et al.
Published: (1993)

Defective presentation to class I-restricted cytotoxic T lymphocytes in vaccinia-infected cells is overcome by enhanced degradation of antigen.
by: Townsend, A, et al.
Published: (1988)

A 15 amino acid fragment of influenza nucleoprotein synthesized in the cytoplasm is presented to class I-restricted cytotoxic T lymphocytes.
by: Gould, K, et al.
Published: (1989)

Cytotoxic T lymphocytes recognize influenza haemagglutinin that lacks a signal sequence
by: Townsend, A, et al.
Published: (1986)

Mouse H-2(k)-restricted cytotoxic T cells recognize antigenic determinants in both the HA1 and HA2 subunits of the influenza A/PR/8/34 hemagglutinin
by: Gould, K, et al.
Published: (1987)

Antigen recognition by class I-restricted T lymphocytes.
by: Townsend, A, et al.
Published: (1989)

Use of synthetic peptides of influenza nucleoprotein to define epitopes recognized by class I-restricted cytotoxic T lymphocytes.
by: Bastin, J, et al.
Published: (1987)

HIV-1 gag-specific cytotoxic T lymphocytes defined with recombinant vaccinia virus and synthetic peptides.
by: Nixon, D, et al.
Published: (1988)

Relationship Between SerpinB9 and Tumors and Research Progress of SerpinB9 in Skin Tumors
by: ZHANG Shan, et al.
Published: (2022-09-01)

Recognition of influenza virus proteins by cytotoxic T lymphocytes.
by: Townsend, A, et al.
Published: (1989)

Epitope-Specific Anti-SerpinB3 Antibodies for SerpinB3 Recognition and Biological Activity Inhibition
by: Alessandra Biasiolo, et al.
Published: (2023-04-01)

Recombinant vaccinia viruses for the characterization of Plasmodium falciparum-specific cytotoxic T lymphocytes: recognition of processed antigen despite limited re-stimulation efficacy.
by: Aidoo, M, et al.
Published: (1997)

An antigen processing polymorphism revealed by HLA-B8-restricted cytotoxic T lymphocytes which does not correlate with TAP gene polymorphism.
by: Rowland-Jones, S, et al.
Published: (1993)

The Effects of Targeting the Vaccinia Virus B5R Protein to the Endoplasmic Reticulum on Virus Morphogenesis and Dissemination
by: Mathew, E, et al.
Published: (1999)

Recombinant modified vaccinia virus Ankara efficiently restimulates human cytotoxic T lymphocytes in vitro.
by: Dorrell, L, et al.
Published: (2000)

HLA-B63 presents HLA-B57/B58-restricted cytotoxic T-lymphocyte epitopes and is associated with low human immunodeficiency virus load.
by: Frahm, N, et al.
Published: (2005)

Studies on the nature and mechanism of influenza antigen recognition by murine cytotoxic T cells
by: Gould, K, et al.
Published: (1988)

Transcriptome analysis of SerpinB2-deficient breast tumors provides insight into deciphering SerpinB2-mediated roles in breast cancer progression
by: Yin Ji Piao, et al.
Published: (2022-06-01)

Identification of a novel HLA-B*3501-restricted cytotoxic T lymphocyte epitope using overlapping peptides.
by: Goulder, P, et al.
Published: (1997)

Combined structural and immunological refinement of HIV-1 HLA-B8-restricted cytotoxic T lymphocyte epitopes.
by: Goulder, P, et al.
Published: (1997)

Recognition of antigen and superantigen by cytotoxic lymphocytes
by: Bowness, P, et al.
Published: (1993)

CD8 independence and specificity of cytotoxic T lymphocytes restricted by HLA-Aw68.1.
by: Cerundolo, V, et al.
Published: (1991)

Deletion of Vaccinia Virus A40R Gene Improves the Immunogenicity of the HIV-1 Vaccine Candidate MVA-B
by: Patricia Pérez, et al.
Published: (2020-02-01)

Identification of a novel HLA B*57 restricted cytotoxic T-lymphocyte epitope within HIV-1 rev.
by: Makadzange, A, et al.
Published: (2006)

Conservation of T cell receptor usage by HLA B27-restricted influenza-specific cytotoxic T lymphocytes suggests a general pattern for antigen-specific major histocompatibility complex class I-restricted responses.
by: Bowness, P, et al.
Published: (1993)

Cytotoxic T lymphocytes form an antigen-independent ring junction
by: Somersalo, K, et al.
Published: (2004)

Cytotoxic T lymphocytes form an antigen-independent ring junction.
by: Somersalo, K, et al.
Published: (2004)

Direct triggering of B lymphocytes by insolubilized antigen.
by: Feldmann, M, et al.
Published: (1974)

Augmented B lymphocyte response to antigen in the absence of antigen-induced B lymphocyte signaling in an IgG-transgenic mouse line.
by: Rong-Yong Man, et al.
Published: (2010-01-01)

Induction of CD8+ T-lymphocyte responses to a secreted antigen of Mycobacterium tuberculosis by an attenuated vaccinia virus.
by: Feng, C, et al.
Published: (2001)

Serpin B9 controls tumor cell killing by CAR T cells
by: Zsolt Sebestyen, et al.
Published: (2023-03-01)

Asymmetric synthesis of cytotoxic sponge metabolites R-strongylodiols A and B
by: Kirkham, J, et al.
Published: (2004)

Clustered mutations in HIV-1 gag are consistently required for escape from HLA-B27-restricted cytotoxic T lymphocyte responses
by: Kelleher, A, et al.
Published: (2001)

Clustered mutations in HIV-1 gag are consistently required for escape from HLA-B27-restricted cytotoxic T lymphocyte responses.
by: Kelleher, A, et al.
Published: (2001)

Vaccinia Virus Gene B7R Encodes an 18-kDa Protein That is Resident in the Endoplasmic Reticulum and Affects Virus Virulence
by: Price, N, et al.
Published: (2000)

Rendezvous with Vaccinia Virus in the Post-smallpox Era: R&D Advances
by: Yuxiang Wang
Published: (2023-08-01)

RBM4 regulates cellular senescence via miR1244/SERPINE1 axis
by: Luning Wang, et al.
Published: (2023-01-01)

SerpinB3/4 Expression Is Associated with Poor Prognosis in Patients with Cholangiocarcinoma
by: Andrea Martini, et al.
Published: (2024-01-01)

SerpinB3 administration protects liver against ischemia-reperfusion injury
by: Cristian Turato, et al.
Published: (2022-10-01)

Asymmetric synthesis of cytotoxic sponge metabolites R-strongylodiols A and B and an analogue
by: Kirkham, J, et al.
Published: (2005)