Quadrupole-time-of-flight mass spectrometer modified for higher-energy dissociation reduces protein assemblies to peptide fragments

The gas-phase dissociation of protein assemblies is becoming crucial for the application of mass spectrometry to structural biology. However certain aspects of the dissociation mechanism remain elusive. Moreover, many protein complexes resist dissociation at the energies accessible with current inst...

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Detalhes bibliográficos
Main Authors: Benesch, J, Ruotolo, B, Sobott, F, Robinson, C, al., E
Formato: Journal article
Idioma:English
Publicado em: American Chemical Society 2009

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