Quadrupole-time-of-flight mass spectrometer modified for higher-energy dissociation reduces protein assemblies to peptide fragments

Quadrupole-time-of-flight mass spectrometer modified for higher-energy dissociation reduces protein assemblies to peptide fragments

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The gas-phase dissociation of protein assemblies is becoming crucial for the application of mass spectrometry to structural biology. However certain aspects of the dissociation mechanism remain elusive. Moreover, many protein complexes resist dissociation at the energies accessible with current inst...

书目详细资料
Main Authors:	Benesch, J, Ruotolo, B, Sobott, F, Robinson, C, al., E
格式:	Journal article
语言:	English
出版:	American Chemical Society 2009

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