Nascent RNA antagonizes the interaction of a set of regulatory proteins with chromatin

A number of regulatory factors are recruited to chromatin by specialized RNAs. Whether RNA has a more general role in regulating the interaction of proteins with chromatin has not been determined. We used proteomics methods to measure the global impact of nascent RNA on chromatin in embryonic stem c...

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Hlavní autoři: Skalska, L, Begley, V, Beltran, M, Lukauskas, S, Khandelwal, G, Faull, P, Bhamra, A, Tavares, M, Wellman, R, Tvardovskiy, A, Foster, BM, Ruiz de Los Mozos, I, Herrero, J, Surinova, S, Snijders, AP, Bartke, T, Jenner, RG
Médium: Journal article
Jazyk:English
Vydáno: Cell Press 2021