Suppression of tumour necrosis factor production from mononuclear cells by a novel synthetic compound, CLX-090717.

Suppression of tumour necrosis factor production from mononuclear cells by a novel synthetic compound, CLX-090717.

OBJECTIVES: To evaluate the clinical efficacy of a novel synthetic peroxisome proliferator-activated receptor gamma (PPAR-gamma) agonist, CLX-090717, in several in vitro cell culture systems and murine CIA, an experimental model of RA. METHODS: Peripheral blood monocytes purified by elutriation, an...

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Bibliographic Details
Main Authors:	Sumariwalla, P, Palmer, C, Pickford, L, Feldmann, M, Foxwell, B, Brennan, F
Format:	Journal article
Language:	English
Published:	2009

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