Notch3 signalling promotes tumour growth in colorectal cancer.

Increased Notch1 activity has been observed in intestinal tumours, partially accomplished by β-catenin-mediated up-regulation of the Notch ligand Jagged-1. Whether further mechanisms of Notch activation exist and other Notch receptors might be involved is unclear. Microarray data indicated that Notc...

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Những tác giả chính: Serafin, V, Persano, L, Moserle, L, Esposito, G, Ghisi, M, Curtarello, M, Bonanno, L, Masiero, M, Ribatti, D, Stürzl, M, Naschberger, E, Croner, R, Jubb, A, Harris, A, Koeppen, H, Amadori, A, Indraccolo, S
Định dạng: Journal article
Ngôn ngữ:English
Được phát hành: 2011