Breathing life into pathogens: the influence of oxygen on bacterial virulence and host responses in the gastrointestinal tract.
The gastrointestinal tract provides a variety of environmental challenges to any bacterium seeking to successfully colonize or cause disease in a host. A major obstacle is the varied oxygen concentrations encountered at different sites in the intestine. Here we review the mechanisms bacterial pathog...
| Main Authors: | , , , |
|---|---|
| Format: | Journal article |
| Language: | English |
| Published: |
2011
|
| _version_ | 1826278074934624256 |
|---|---|
| author | Marteyn, B Scorza, F Sansonetti, P Tang, C |
| author_facet | Marteyn, B Scorza, F Sansonetti, P Tang, C |
| author_sort | Marteyn, B |
| collection | OXFORD |
| description | The gastrointestinal tract provides a variety of environmental challenges to any bacterium seeking to successfully colonize or cause disease in a host. A major obstacle is the varied oxygen concentrations encountered at different sites in the intestine. Here we review the mechanisms bacterial pathogens utilize to sense oxygen within the gastrointestinal tract, and recent insights into how this acts as a signal to trigger virulence and to modulate host responses. |
| first_indexed | 2024-03-06T23:38:30Z |
| format | Journal article |
| id | oxford-uuid:6e7c3a71-0e8a-4643-9677-89d24eca4fbb |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-06T23:38:30Z |
| publishDate | 2011 |
| record_format | dspace |
| spelling | oxford-uuid:6e7c3a71-0e8a-4643-9677-89d24eca4fbb2022-03-26T19:24:46ZBreathing life into pathogens: the influence of oxygen on bacterial virulence and host responses in the gastrointestinal tract.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:6e7c3a71-0e8a-4643-9677-89d24eca4fbbEnglishSymplectic Elements at Oxford2011Marteyn, BScorza, FSansonetti, PTang, CThe gastrointestinal tract provides a variety of environmental challenges to any bacterium seeking to successfully colonize or cause disease in a host. A major obstacle is the varied oxygen concentrations encountered at different sites in the intestine. Here we review the mechanisms bacterial pathogens utilize to sense oxygen within the gastrointestinal tract, and recent insights into how this acts as a signal to trigger virulence and to modulate host responses. |
| spellingShingle | Marteyn, B Scorza, F Sansonetti, P Tang, C Breathing life into pathogens: the influence of oxygen on bacterial virulence and host responses in the gastrointestinal tract. |
| title | Breathing life into pathogens: the influence of oxygen on bacterial virulence and host responses in the gastrointestinal tract. |
| title_full | Breathing life into pathogens: the influence of oxygen on bacterial virulence and host responses in the gastrointestinal tract. |
| title_fullStr | Breathing life into pathogens: the influence of oxygen on bacterial virulence and host responses in the gastrointestinal tract. |
| title_full_unstemmed | Breathing life into pathogens: the influence of oxygen on bacterial virulence and host responses in the gastrointestinal tract. |
| title_short | Breathing life into pathogens: the influence of oxygen on bacterial virulence and host responses in the gastrointestinal tract. |
| title_sort | breathing life into pathogens the influence of oxygen on bacterial virulence and host responses in the gastrointestinal tract |
| work_keys_str_mv | AT marteynb breathinglifeintopathogenstheinfluenceofoxygenonbacterialvirulenceandhostresponsesinthegastrointestinaltract AT scorzaf breathinglifeintopathogenstheinfluenceofoxygenonbacterialvirulenceandhostresponsesinthegastrointestinaltract AT sansonettip breathinglifeintopathogenstheinfluenceofoxygenonbacterialvirulenceandhostresponsesinthegastrointestinaltract AT tangc breathinglifeintopathogenstheinfluenceofoxygenonbacterialvirulenceandhostresponsesinthegastrointestinaltract |