Chemical space mimicry for drug discovery
We describe a new library generation method, Machine-based Identification of Molecules Inside Characterized Space (MIMICS), that generates sets of molecules inspired by a text-based input. MIMICS-generated libraries were found to preserve distributions of properties while simultaneously increasing s...
Հիմնական հեղինակներ: | Yuan, W, Jiang, D, Nambiar, D, Liew, L, Hay, M, Bloomstein, J, Lu, P, Turner, B, Le, Q, Tibshirani, R, Khatri, P, Moloney, M, Koong, A |
---|---|
Ձևաչափ: | Journal article |
Լեզու: | English |
Հրապարակվել է: |
American Chemical Society
2017
|
Նմանատիպ նյութեր
-
3D In Vitro Human Organ Mimicry Devices for Drug Discovery, Development, and Assessment
: Aida Rodriguez-Garcia, և այլն
Հրապարակվել է: (2020-01-01) -
Systemic evolutionary chemical space exploration for drug discovery
: Chong Lu, և այլն
Հրապարակվել է: (2022-04-01) -
Part II: New frontiers in antibacterial drug discovery
: Moloney, M
Հրապարակվել է: (2016) -
Part I: New frontiers in antibacterial drug discovery
: Moloney, M
Հրապարակվել է: (2016) -
The iterative application of a large chemical space in the drug discovery process
: Olena V. Savych, և այլն
Հրապարակվել է: (2021-12-01)