HAPGEN2: simulation of multiple disease SNPs.

HAPGEN2: simulation of multiple disease SNPs.

MOTIVATION: Performing experiments with simulated data is an inexpensive approach to evaluating competing experimental designs and analysis methods in genome-wide association studies. Simulation based on resampling known haplotypes is fast and efficient and can produce samples with patterns of linka...

Podrobná bibliografie
Hlavní autoři:	Su, Z, Marchini, J, Donnelly, P
Médium:	Journal article
Jazyk:	English
Vydáno:	2011

Podobné jednotky

Genome-wide strategies for detecting multiple loci that influence complex diseases.
Autor: Marchini, J, a další
Vydáno: (2005)

Association scan of 14,500 nonsynonymous SNPs in four diseases identifies autoimmunity variants.
Autor: Burton, P, a další
Vydáno: (2007)

Estimation and partitioning of polygenic variation captured by common SNPs for Alzheimer's disease, multiple sclerosis and endometriosis.
Autor: Lee, S, a další
Vydáno: (2013)

Estimating the proportion of variation in susceptibility to multiple sclerosis captured by common SNPs
Autor: Watson, C, a další
Vydáno: (2012)

Genetically indistinguishable SNPs and their influence on inferring the location of disease-associated variants.
Autor: Lawrence, R, a další
Vydáno: (2005)

Gene associations - SNPs and function.
Autor: Ebers, G
Vydáno: (2011)

Multiple SNPs downregulate gene expression of Matrix Metallopeptidase 2 in MCF7 breast cancer cells
Autor: Ahmad Suhaimi, Shafinah, a další
Vydáno: (2024)

Neuregulin 1 transcripts are differentially expressed in schizophrenia and regulated by 5' SNPs associated with the disease.
Autor: Law, A, a další
Vydáno: (2006)

Use of Tag single nucleotide polymorphisms (SNPs) to screen PTPN21: no association with Graves' disease.
Autor: Zeitlin, A, a další
Vydáno: (2006)

Scientific software: Seeing the SNPs between us
Autor: Buckingham, S
Vydáno: (2008)

The role of SNPs in the management of cancer in the broader population
Autor: Kitchen-Smith, I
Vydáno: (2020)

Fast genotyping of known SNPs through approximate
Autor: Shajii, Ariya, a další
Vydáno: (2018)

Proteome-wide analysis of disease-associated SNPs that show allele-specific transcription factor binding
Autor: Butter, F, a další
Vydáno: (2012)

CYTOKINE GENE SNPS ARE ASSOCIATED WITH SEVERE MALARIA IN VIETNAM
Autor: Quyen, N, a další
Vydáno: (2009)

Neuregulin 1 (NRG1) transcripts are differentially expressed in schizophrenia and regulated by 5 ' SNPS associated with the disease
Autor: Law, A, a další
Vydáno: (2005)

Breast cancer susceptibility : accessing newly discovered SNPs
Autor: Loh, Eunice Ting Wei
Vydáno: (2010)

Genotype prediction using a dense map of SNPs.
Autor: Evans, D, a další
Vydáno: (2004)

Genetic association of SNPs in the FTO gene and predisposition to obesity in Malaysian Malays
Autor: Apalasamy, Y.D., a další
Vydáno: (2012)

Designing genome-wide association studies: sample size, power, imputation, and the choice of genotyping chip.
Autor: Spencer, C, a další
Vydáno: (2009)

Association of the interleukin-2 receptor alpha (IL-2Ralpha)/CD25 gene region with Graves' disease using a multilocus test and tag SNPs.
Autor: Brand, O, a další
Vydáno: (2007)

No genetic association between attention-deficit/hyperactivity disorder (ADHD) and Parkinson’s disease in nine ADHD candidate SNPs
Autor: Geissler, J, a další
Vydáno: (2017)

Low penetrance breast cancer predisposition SNPs are site specific.
Autor: Mcinerney, N, a další
Vydáno: (2009)

FROM SNPs TO FUNCTION: TRANSCRIPTIONAL REGULATION OF RUNX3 IN ANKYLOSING SPONDYLITIS
Autor: Vecellio, M, a další
Vydáno: (2014)

Susceptibility to coronary artery disease and diabetes is encoded by distinct, tightly linked SNPs in the ANRIL locus on chromosome 9p.
Autor: Broadbent, H, a další
Vydáno: (2008)

Susceptibility to coronary artery disease and diabetes is encoded by distinct, tightly linked SNPs in the ANRIL locus on chromosome 9p
Autor: Broadbent, H, a další
Vydáno: (2008)

Linkage disequilibrium at PPARG and other genes assessed with dense sets of SNPs..
Autor: Hirschhorn, J, a další
Vydáno: (2001)

LD and Haplotype Block Analysis of SNPs on CAST Gene in Boerka Goat
Autor: Maharani, Dyah, a další
Vydáno: (2019)

cnvHap: an integrative population and haplotype-based multiplatform model of SNPs and CNVs.
Autor: Coin, L, a další
Vydáno: (2010)

Geographical distribution of selected and putatively neutral SNPs in Southeast Asian malaria parasites.
Autor: Anderson, T, a další
Vydáno: (2005)

A gene centric association study of 1500 SNPs in the chromosome 2q autism susceptibility locus
Autor: Bacchelli, E, a další
Vydáno: (2006)

Effective selection of informative SNPs and classification on the HapMap genotype data
Autor: Zhou, Nina., a další
Vydáno: (2012)

Accurate detection of SNPs using base-specific cleavage and mass spectrometry
Autor: Sun, Ruimin, a další
Vydáno: (2013)

Caspase-8 gene SNPs in prostate cancer susceptibility a replication study
Autor: Parry, M, a další
Vydáno: (2010)

A Bayesian Method for Detecting and Characterizing Allelic Heterogeneity and Boosting Signals in Genome-Wide Association Studies
Autor: Su, Z, a další
Vydáno: (2010)

Assignment of Y-chromosomal SNPs found in Japanese population to Y-chromosomal haplogroup tree
Autor: Naitoh, S., a další
Vydáno: (2013)

Private genomes and public SNPs: homomorphic encryption of genotypes and phenotypes for shared quantitative genetics
Autor: Mott, R, a další
Vydáno: (2020)

The study of six SNPS in LCT regulatory region and it's association to lactose intolerance in Sabah
Autor: Nur Ashikhin Gandah
Vydáno: (2014)

Synthesis of SnPS3 nanosheets for anode in lithium ion battery application
Autor: Wirahara, Jonathan Kenichi
Vydáno: (2019)

Detection of protocadherinX/Y SNPs in patients with schizophrenia and other family members
Autor: Giouzeli, M, a další
Vydáno: (2002)

ANKYLOSING SPONDYLITIS-ASSOCIATED SNPS AT THE IL23R-IL12RB2 INTERGENIC REGION ARE FUNCTIONALLY IMPORTANT
Autor: Roberts, A, a další
Vydáno: (2014)