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Expression of a membrane associated CC-chemokine inhibitor protein reduces in vitro macrophage chemotaxis to CC chemokines

Expression of a membrane associated CC-chemokine inhibitor protein reduces in vitro macrophage chemotaxis to CC chemokines

Detalles Bibliográficos
Main Authors: McNeill, E, White, G, Patel, J, Greaves, D, Channon, K
Formato: Conference item
Publicado: 2010
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  • Contrasting in vitro vs. in vivo effects of a cell membrane-specific CC-chemokine binding protein on macrophage chemotaxis.
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  • Membrane-bound CC chemokine inhibitor 35K provides localized inhibition of CC chemokine activity in vitro and in vivo.
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  • Site-directed mutagenesis of the CC chemokine binding protein 35K-Fc reveals residues essential for activity and mutations that increase the potency of CC chemokine blockade.
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    Publicado: (2004)

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